ERN1 knockdown modifies the impact of glucose and glutamine deprivations on the expression of EDN1 and its receptors in glioma cells
Objective. The aim of the present investigation was to study the impact of glucose and gluta-mine deprivations on the expression of genes encoding EDN1 (endothelin-1), its cognate receptors (EDNRA and EDNRB), and ECE1 (endothelin converting enzyme 1) in U87 glioma cells in response to knockdown of E...
Guardado en:
| Autores principales: | , , , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Sciendo
2021
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/05798c7df2cc4925be183482a388f64d |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:05798c7df2cc4925be183482a388f64d |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:05798c7df2cc4925be183482a388f64d2021-12-02T17:49:33ZERN1 knockdown modifies the impact of glucose and glutamine deprivations on the expression of EDN1 and its receptors in glioma cells1336-032910.2478/enr-2021-0009https://doaj.org/article/05798c7df2cc4925be183482a388f64d2021-04-01T00:00:00Zhttps://doi.org/10.2478/enr-2021-0009https://doaj.org/toc/1336-0329Objective. The aim of the present investigation was to study the impact of glucose and gluta-mine deprivations on the expression of genes encoding EDN1 (endothelin-1), its cognate receptors (EDNRA and EDNRB), and ECE1 (endothelin converting enzyme 1) in U87 glioma cells in response to knockdown of ERN1 (endoplasmic reticulum to nucleus signaling 1), a major signaling pathway of endoplasmic reticulum stress, for evaluation of their possible implication in the control of glioma growth through ERN1 and nutrient limitations.Minchenko Dmytro O.Khita Olena O.Tsymbal Dariia O.Viletska Yuliia M.Sliusar Myroslava Y.Yefimova Yuliia V.Levadna Liudmyla O.Krasnytska Dariia A.Minchenko Oleksandr H.Sciendoarticleern1 knockdownmrna expressionedn1ednraednrbece1glucose and glutamine deprivationsu87 glioma cellsDiseases of the endocrine glands. Clinical endocrinologyRC648-665ENEndocrine Regulations, Vol 55, Iss 2, Pp 72-82 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
ern1 knockdown mrna expression edn1 ednra ednrb ece1 glucose and glutamine deprivations u87 glioma cells Diseases of the endocrine glands. Clinical endocrinology RC648-665 |
| spellingShingle |
ern1 knockdown mrna expression edn1 ednra ednrb ece1 glucose and glutamine deprivations u87 glioma cells Diseases of the endocrine glands. Clinical endocrinology RC648-665 Minchenko Dmytro O. Khita Olena O. Tsymbal Dariia O. Viletska Yuliia M. Sliusar Myroslava Y. Yefimova Yuliia V. Levadna Liudmyla O. Krasnytska Dariia A. Minchenko Oleksandr H. ERN1 knockdown modifies the impact of glucose and glutamine deprivations on the expression of EDN1 and its receptors in glioma cells |
| description |
Objective. The aim of the present investigation was to study the impact of glucose and gluta-mine deprivations on the expression of genes encoding EDN1 (endothelin-1), its cognate receptors (EDNRA and EDNRB), and ECE1 (endothelin converting enzyme 1) in U87 glioma cells in response to knockdown of ERN1 (endoplasmic reticulum to nucleus signaling 1), a major signaling pathway of endoplasmic reticulum stress, for evaluation of their possible implication in the control of glioma growth through ERN1 and nutrient limitations. |
| format |
article |
| author |
Minchenko Dmytro O. Khita Olena O. Tsymbal Dariia O. Viletska Yuliia M. Sliusar Myroslava Y. Yefimova Yuliia V. Levadna Liudmyla O. Krasnytska Dariia A. Minchenko Oleksandr H. |
| author_facet |
Minchenko Dmytro O. Khita Olena O. Tsymbal Dariia O. Viletska Yuliia M. Sliusar Myroslava Y. Yefimova Yuliia V. Levadna Liudmyla O. Krasnytska Dariia A. Minchenko Oleksandr H. |
| author_sort |
Minchenko Dmytro O. |
| title |
ERN1 knockdown modifies the impact of glucose and glutamine deprivations on the expression of EDN1 and its receptors in glioma cells |
| title_short |
ERN1 knockdown modifies the impact of glucose and glutamine deprivations on the expression of EDN1 and its receptors in glioma cells |
| title_full |
ERN1 knockdown modifies the impact of glucose and glutamine deprivations on the expression of EDN1 and its receptors in glioma cells |
| title_fullStr |
ERN1 knockdown modifies the impact of glucose and glutamine deprivations on the expression of EDN1 and its receptors in glioma cells |
| title_full_unstemmed |
ERN1 knockdown modifies the impact of glucose and glutamine deprivations on the expression of EDN1 and its receptors in glioma cells |
| title_sort |
ern1 knockdown modifies the impact of glucose and glutamine deprivations on the expression of edn1 and its receptors in glioma cells |
| publisher |
Sciendo |
| publishDate |
2021 |
| url |
https://doaj.org/article/05798c7df2cc4925be183482a388f64d |
| work_keys_str_mv |
AT minchenkodmytroo ern1knockdownmodifiestheimpactofglucoseandglutaminedeprivationsontheexpressionofedn1anditsreceptorsingliomacells AT khitaolenao ern1knockdownmodifiestheimpactofglucoseandglutaminedeprivationsontheexpressionofedn1anditsreceptorsingliomacells AT tsymbaldariiao ern1knockdownmodifiestheimpactofglucoseandglutaminedeprivationsontheexpressionofedn1anditsreceptorsingliomacells AT viletskayuliiam ern1knockdownmodifiestheimpactofglucoseandglutaminedeprivationsontheexpressionofedn1anditsreceptorsingliomacells AT sliusarmyroslavay ern1knockdownmodifiestheimpactofglucoseandglutaminedeprivationsontheexpressionofedn1anditsreceptorsingliomacells AT yefimovayuliiav ern1knockdownmodifiestheimpactofglucoseandglutaminedeprivationsontheexpressionofedn1anditsreceptorsingliomacells AT levadnaliudmylao ern1knockdownmodifiestheimpactofglucoseandglutaminedeprivationsontheexpressionofedn1anditsreceptorsingliomacells AT krasnytskadariiaa ern1knockdownmodifiestheimpactofglucoseandglutaminedeprivationsontheexpressionofedn1anditsreceptorsingliomacells AT minchenkooleksandrh ern1knockdownmodifiestheimpactofglucoseandglutaminedeprivationsontheexpressionofedn1anditsreceptorsingliomacells |
| _version_ |
1718379389149773824 |