Stable MOB1 interaction with Hippo/MST is not essential for development and tissue growth control

The Hippo tumor suppressor pathway is essential for development and tissue growth control. Here the authors employ a multi-disciplinary approach to characterize the interactions of the three Hippo kinases with the signaling adaptor MOB1 and show how they differently affect development, tissue growth...

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Autores principales: Yavuz Kulaberoglu, Kui Lin, Maxine Holder, Zhongchao Gai, Marta Gomez, Belul Assefa Shifa, Merdiye Mavis, Lily Hoa, Ahmad A. D. Sharif, Celia Lujan, Ewan St. John Smith, Ivana Bjedov, Nicolas Tapon, Geng Wu, Alexander Hergovich
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Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/057c5004ddb54609858a2e780a18b291
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spelling oai:doaj.org-article:057c5004ddb54609858a2e780a18b2912021-12-02T17:06:13ZStable MOB1 interaction with Hippo/MST is not essential for development and tissue growth control10.1038/s41467-017-00795-y2041-1723https://doaj.org/article/057c5004ddb54609858a2e780a18b2912017-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00795-yhttps://doaj.org/toc/2041-1723The Hippo tumor suppressor pathway is essential for development and tissue growth control. Here the authors employ a multi-disciplinary approach to characterize the interactions of the three Hippo kinases with the signaling adaptor MOB1 and show how they differently affect development, tissue growth and tumor suppression.Yavuz KulaberogluKui LinMaxine HolderZhongchao GaiMarta GomezBelul Assefa ShifaMerdiye MavisLily HoaAhmad A. D. SharifCelia LujanEwan St. John SmithIvana BjedovNicolas TaponGeng WuAlexander HergovichNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yavuz Kulaberoglu
Kui Lin
Maxine Holder
Zhongchao Gai
Marta Gomez
Belul Assefa Shifa
Merdiye Mavis
Lily Hoa
Ahmad A. D. Sharif
Celia Lujan
Ewan St. John Smith
Ivana Bjedov
Nicolas Tapon
Geng Wu
Alexander Hergovich
Stable MOB1 interaction with Hippo/MST is not essential for development and tissue growth control
description The Hippo tumor suppressor pathway is essential for development and tissue growth control. Here the authors employ a multi-disciplinary approach to characterize the interactions of the three Hippo kinases with the signaling adaptor MOB1 and show how they differently affect development, tissue growth and tumor suppression.
format article
author Yavuz Kulaberoglu
Kui Lin
Maxine Holder
Zhongchao Gai
Marta Gomez
Belul Assefa Shifa
Merdiye Mavis
Lily Hoa
Ahmad A. D. Sharif
Celia Lujan
Ewan St. John Smith
Ivana Bjedov
Nicolas Tapon
Geng Wu
Alexander Hergovich
author_facet Yavuz Kulaberoglu
Kui Lin
Maxine Holder
Zhongchao Gai
Marta Gomez
Belul Assefa Shifa
Merdiye Mavis
Lily Hoa
Ahmad A. D. Sharif
Celia Lujan
Ewan St. John Smith
Ivana Bjedov
Nicolas Tapon
Geng Wu
Alexander Hergovich
author_sort Yavuz Kulaberoglu
title Stable MOB1 interaction with Hippo/MST is not essential for development and tissue growth control
title_short Stable MOB1 interaction with Hippo/MST is not essential for development and tissue growth control
title_full Stable MOB1 interaction with Hippo/MST is not essential for development and tissue growth control
title_fullStr Stable MOB1 interaction with Hippo/MST is not essential for development and tissue growth control
title_full_unstemmed Stable MOB1 interaction with Hippo/MST is not essential for development and tissue growth control
title_sort stable mob1 interaction with hippo/mst is not essential for development and tissue growth control
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/057c5004ddb54609858a2e780a18b291
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