Stable MOB1 interaction with Hippo/MST is not essential for development and tissue growth control
The Hippo tumor suppressor pathway is essential for development and tissue growth control. Here the authors employ a multi-disciplinary approach to characterize the interactions of the three Hippo kinases with the signaling adaptor MOB1 and show how they differently affect development, tissue growth...
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Nature Portfolio
2017
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oai:doaj.org-article:057c5004ddb54609858a2e780a18b2912021-12-02T17:06:13ZStable MOB1 interaction with Hippo/MST is not essential for development and tissue growth control10.1038/s41467-017-00795-y2041-1723https://doaj.org/article/057c5004ddb54609858a2e780a18b2912017-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00795-yhttps://doaj.org/toc/2041-1723The Hippo tumor suppressor pathway is essential for development and tissue growth control. Here the authors employ a multi-disciplinary approach to characterize the interactions of the three Hippo kinases with the signaling adaptor MOB1 and show how they differently affect development, tissue growth and tumor suppression.Yavuz KulaberogluKui LinMaxine HolderZhongchao GaiMarta GomezBelul Assefa ShifaMerdiye MavisLily HoaAhmad A. D. SharifCelia LujanEwan St. John SmithIvana BjedovNicolas TaponGeng WuAlexander HergovichNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-16 (2017) |
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Science Q |
spellingShingle |
Science Q Yavuz Kulaberoglu Kui Lin Maxine Holder Zhongchao Gai Marta Gomez Belul Assefa Shifa Merdiye Mavis Lily Hoa Ahmad A. D. Sharif Celia Lujan Ewan St. John Smith Ivana Bjedov Nicolas Tapon Geng Wu Alexander Hergovich Stable MOB1 interaction with Hippo/MST is not essential for development and tissue growth control |
description |
The Hippo tumor suppressor pathway is essential for development and tissue growth control. Here the authors employ a multi-disciplinary approach to characterize the interactions of the three Hippo kinases with the signaling adaptor MOB1 and show how they differently affect development, tissue growth and tumor suppression. |
format |
article |
author |
Yavuz Kulaberoglu Kui Lin Maxine Holder Zhongchao Gai Marta Gomez Belul Assefa Shifa Merdiye Mavis Lily Hoa Ahmad A. D. Sharif Celia Lujan Ewan St. John Smith Ivana Bjedov Nicolas Tapon Geng Wu Alexander Hergovich |
author_facet |
Yavuz Kulaberoglu Kui Lin Maxine Holder Zhongchao Gai Marta Gomez Belul Assefa Shifa Merdiye Mavis Lily Hoa Ahmad A. D. Sharif Celia Lujan Ewan St. John Smith Ivana Bjedov Nicolas Tapon Geng Wu Alexander Hergovich |
author_sort |
Yavuz Kulaberoglu |
title |
Stable MOB1 interaction with Hippo/MST is not essential for development and tissue growth control |
title_short |
Stable MOB1 interaction with Hippo/MST is not essential for development and tissue growth control |
title_full |
Stable MOB1 interaction with Hippo/MST is not essential for development and tissue growth control |
title_fullStr |
Stable MOB1 interaction with Hippo/MST is not essential for development and tissue growth control |
title_full_unstemmed |
Stable MOB1 interaction with Hippo/MST is not essential for development and tissue growth control |
title_sort |
stable mob1 interaction with hippo/mst is not essential for development and tissue growth control |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/057c5004ddb54609858a2e780a18b291 |
work_keys_str_mv |
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1718381655248338944 |