Dual roles of AMAP1 in the transcriptional regulation and intracellular trafficking of carbonic anhydrase IX
Background: The cell-surface enzyme carbonic anhydrase IX (CAIX/CA9) promotes tumor growth, survival, invasion, and metastasis, mainly via its pH-regulating functions. Owing to its tumor-specific expression, CAIX-targeting antibodies/chemicals are utilized for therapeutic and diagnostic purposes. Ho...
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| Format: | article |
| Langue: | EN |
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Elsevier
2022
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| Accès en ligne: | https://doaj.org/article/05815bf77f9c46e689306ffd78f18c81 |
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