Prevalence of hypothyroidism in patients with type 2 diabetes mellitus and hypertension in India: a cross-sectional observational study

Pradeep Talwalkar,1 Vaishali Deshmukh,2 Milind Bhole3 1Endocrinology, Talwalkar Diabetes Clinic, Mumbai, India; 2Endocrinology, Shree Hospital, Pune, India; 3Medical Affairs, Abbott India Ltd, Mumbai, India Purpose: To determine the prevalence of hypothyroidism in patients with type 2 diabetes melli...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Talwalkar P, Deshmukh V, Bhole M
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2019
Materias:	Hypertension Hypothyroidism Prevalence Type 2 Diabetes Mellitus Specialties of internal medicine RC581-951
Acceso en línea:	https://doaj.org/article/05863aab2ca4443d80ae978a9a575d4d
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:05863aab2ca4443d80ae978a9a575d4d
record_format	dspace
spelling	oai:doaj.org-article:05863aab2ca4443d80ae978a9a575d4d2021-12-02T04:06:46ZPrevalence of hypothyroidism in patients with type 2 diabetes mellitus and hypertension in India: a cross-sectional observational study1178-7007https://doaj.org/article/05863aab2ca4443d80ae978a9a575d4d2019-03-01T00:00:00Zhttps://www.dovepress.com/prevalence-of-hypothyroidism-in-patients-with-type-2-diabetes-mellitus-peer-reviewed-article-DMSOhttps://doaj.org/toc/1178-7007Pradeep Talwalkar,1 Vaishali Deshmukh,2 Milind Bhole3 1Endocrinology, Talwalkar Diabetes Clinic, Mumbai, India; 2Endocrinology, Shree Hospital, Pune, India; 3Medical Affairs, Abbott India Ltd, Mumbai, India Purpose: To determine the prevalence of hypothyroidism in patients with type 2 diabetes mellitus (T2DM), hypertension, and both T2DM and hypertension (T2DM + hypertension) in India. Patients and methods: In this cross-sectional observational study, adult patients with an established or newly diagnosed T2DM, hypertension, and T2DM + hypertension who were visiting their physicians for a routine clinical checkup were enrolled across 29 sites in India. All the patient-related data were extracted from their medical records. The prevalence of hypothyroidism was evaluated by thyroid function test (levels of serum free thyroxine, free triiodothyronine, and thyroid-stimulating hormone [TSH]). The proportion of obese and overweight hypothyroid patients and dose of thyroxine in overt and subclinical hypothyroidism (SCH) cases (as per TSH values) were assessed during the study. The results were summarized by descriptive statistics. Results: A total of 1,508 patients (T2DM: 504; hypertension: 501; T2DM + hypertension: 503) were enrolled in the study. The prevalence of hypothyroidism in patients with T2DM, hypertension, and T2DM + hypertension was 24.8%, 33.5%, and 28.9%, respectively. The overall prevalence of hypothyroidism in T2DM (n=1,002) and hypertension (n=1,001) was 26.9% and 31.2%, respectively. The proportion of obese against overweight hypothyroid patients was higher in all indications (T2DM: 16.5% vs 3.4%; hypertension: 23.8% vs 5.4%; T2DM + hypertension: 21.5% vs 3.8%). A considerable proportion of patients with SCH was prescribed thyroxine in T2DM (61.5%), hypertension (61%), and T2DM + hypertension (62.5%) cases. The most commonly prescribed dose (mean) of thyroxine was 50 and 25 µg for overt hypothyroidism and SCH cases, respectively, in all cohorts. Conclusion: There is a high (>20%) prevalence of hypothyroidism in patients with T2DM, hypertension, and T2DM + hypertension. Screening for hypothyroidism should be routinely considered for early diagnosis and effective management. Keywords: hypertension, hypothyroidism, prevalence, type 2 diabetes mellitusTalwalkar PDeshmukh VBhole MDove Medical PressarticleHypertensionHypothyroidismPrevalenceType 2 Diabetes MellitusSpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol Volume 12, Pp 369-376 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Hypertension Hypothyroidism Prevalence Type 2 Diabetes Mellitus Specialties of internal medicine RC581-951
spellingShingle	Hypertension Hypothyroidism Prevalence Type 2 Diabetes Mellitus Specialties of internal medicine RC581-951 Talwalkar P Deshmukh V Bhole M Prevalence of hypothyroidism in patients with type 2 diabetes mellitus and hypertension in India: a cross-sectional observational study
description	Pradeep Talwalkar,1 Vaishali Deshmukh,2 Milind Bhole3 1Endocrinology, Talwalkar Diabetes Clinic, Mumbai, India; 2Endocrinology, Shree Hospital, Pune, India; 3Medical Affairs, Abbott India Ltd, Mumbai, India Purpose: To determine the prevalence of hypothyroidism in patients with type 2 diabetes mellitus (T2DM), hypertension, and both T2DM and hypertension (T2DM + hypertension) in India. Patients and methods: In this cross-sectional observational study, adult patients with an established or newly diagnosed T2DM, hypertension, and T2DM + hypertension who were visiting their physicians for a routine clinical checkup were enrolled across 29 sites in India. All the patient-related data were extracted from their medical records. The prevalence of hypothyroidism was evaluated by thyroid function test (levels of serum free thyroxine, free triiodothyronine, and thyroid-stimulating hormone [TSH]). The proportion of obese and overweight hypothyroid patients and dose of thyroxine in overt and subclinical hypothyroidism (SCH) cases (as per TSH values) were assessed during the study. The results were summarized by descriptive statistics. Results: A total of 1,508 patients (T2DM: 504; hypertension: 501; T2DM + hypertension: 503) were enrolled in the study. The prevalence of hypothyroidism in patients with T2DM, hypertension, and T2DM + hypertension was 24.8%, 33.5%, and 28.9%, respectively. The overall prevalence of hypothyroidism in T2DM (n=1,002) and hypertension (n=1,001) was 26.9% and 31.2%, respectively. The proportion of obese against overweight hypothyroid patients was higher in all indications (T2DM: 16.5% vs 3.4%; hypertension: 23.8% vs 5.4%; T2DM + hypertension: 21.5% vs 3.8%). A considerable proportion of patients with SCH was prescribed thyroxine in T2DM (61.5%), hypertension (61%), and T2DM + hypertension (62.5%) cases. The most commonly prescribed dose (mean) of thyroxine was 50 and 25 µg for overt hypothyroidism and SCH cases, respectively, in all cohorts. Conclusion: There is a high (>20%) prevalence of hypothyroidism in patients with T2DM, hypertension, and T2DM + hypertension. Screening for hypothyroidism should be routinely considered for early diagnosis and effective management. Keywords: hypertension, hypothyroidism, prevalence, type 2 diabetes mellitus
format	article
author	Talwalkar P Deshmukh V Bhole M
author_facet	Talwalkar P Deshmukh V Bhole M
author_sort	Talwalkar P
title	Prevalence of hypothyroidism in patients with type 2 diabetes mellitus and hypertension in India: a cross-sectional observational study
title_short	Prevalence of hypothyroidism in patients with type 2 diabetes mellitus and hypertension in India: a cross-sectional observational study
title_full	Prevalence of hypothyroidism in patients with type 2 diabetes mellitus and hypertension in India: a cross-sectional observational study
title_fullStr	Prevalence of hypothyroidism in patients with type 2 diabetes mellitus and hypertension in India: a cross-sectional observational study
title_full_unstemmed	Prevalence of hypothyroidism in patients with type 2 diabetes mellitus and hypertension in India: a cross-sectional observational study
title_sort	prevalence of hypothyroidism in patients with type 2 diabetes mellitus and hypertension in india: a cross-sectional observational study
publisher	Dove Medical Press
publishDate	2019
url	https://doaj.org/article/05863aab2ca4443d80ae978a9a575d4d
work_keys_str_mv	AT talwalkarp prevalenceofhypothyroidisminpatientswithtype2diabetesmellitusandhypertensioninindiaacrosssectionalobservationalstudy AT deshmukhv prevalenceofhypothyroidisminpatientswithtype2diabetesmellitusandhypertensioninindiaacrosssectionalobservationalstudy AT bholem prevalenceofhypothyroidisminpatientswithtype2diabetesmellitusandhypertensioninindiaacrosssectionalobservationalstudy
_version_	1718401410019622912

Prevalence of hypothyroidism in patients with type 2 diabetes mellitus and hypertension in India: a cross-sectional observational study

Ejemplares similares