DNA Methyltransferase1 (DNMT1) Isoform3 methylates mitochondrial genome and modulates its biology

Abstract Here we demonstrate localization of the isoform3 of DNA Methyltransferase1 (DNMT1) enzyme to mitochondria, instead of isoform1 as reported earlier. The fused DNMT1-isoform1, reported earlier to localize in mitochondria, surprisingly showed its exclusive presence inside the nucleus after its...

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Autores principales: Sunil Kumar Saini, Kailash Chandra Mangalhara, Gopinath Prakasam, R. N. K. Bamezai
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/05a5af99ff31489f98ba8f2624253fd6
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