Homing in on genomic instability as a therapeutic target in cancer

While genomic instability is a hallmark of cancer, its genetic vulnerabilities remain poorly understood. Identifying strategies that exploit genomic instability to selectively target cancer cells is a central challenge in cancer biology with major implications for anti-cancer drug development.

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Detalles Bibliográficos
Autores principales:	Craig M. Bielski, Barry S. Taylor
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/05aa6b75dc3d45a196bcacb216f9a997
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spelling	oai:doaj.org-article:05aa6b75dc3d45a196bcacb216f9a9972021-12-02T17:23:15ZHoming in on genomic instability as a therapeutic target in cancer10.1038/s41467-021-23965-52041-1723https://doaj.org/article/05aa6b75dc3d45a196bcacb216f9a9972021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23965-5https://doaj.org/toc/2041-1723While genomic instability is a hallmark of cancer, its genetic vulnerabilities remain poorly understood. Identifying strategies that exploit genomic instability to selectively target cancer cells is a central challenge in cancer biology with major implications for anti-cancer drug development.Craig M. BielskiBarry S. TaylorNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-3 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Craig M. Bielski Barry S. Taylor Homing in on genomic instability as a therapeutic target in cancer
description	While genomic instability is a hallmark of cancer, its genetic vulnerabilities remain poorly understood. Identifying strategies that exploit genomic instability to selectively target cancer cells is a central challenge in cancer biology with major implications for anti-cancer drug development.
format	article
author	Craig M. Bielski Barry S. Taylor
author_facet	Craig M. Bielski Barry S. Taylor
author_sort	Craig M. Bielski
title	Homing in on genomic instability as a therapeutic target in cancer
title_short	Homing in on genomic instability as a therapeutic target in cancer
title_full	Homing in on genomic instability as a therapeutic target in cancer
title_fullStr	Homing in on genomic instability as a therapeutic target in cancer
title_full_unstemmed	Homing in on genomic instability as a therapeutic target in cancer
title_sort	homing in on genomic instability as a therapeutic target in cancer
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/05aa6b75dc3d45a196bcacb216f9a997
work_keys_str_mv	AT craigmbielski hominginongenomicinstabilityasatherapeutictargetincancer AT barrystaylor hominginongenomicinstabilityasatherapeutictargetincancer
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Homing in on genomic instability as a therapeutic target in cancer

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