Cardiovascular Imaging and Theranostics in Cardiovascular Pharmacotherapy

Imaging plays a pivotal role in the diagnostic and prognostic assessment of cardiovascular diseases. During the past two decades, there has been an expansion of the available imaging techniques, some of which are now part of routine clinical practice. Cardiovascular imaging of atherosclerosis is a u...

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Autores principales: Mattia Cattaneo, Alberto Froio, Augusto Gallino
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Lenguaje:EN
Publicado: Radcliffe Medical Media 2019
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Acceso en línea:https://doaj.org/article/05ae3bd5e640416c8fbc9c9c1e3ada32
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spelling oai:doaj.org-article:05ae3bd5e640416c8fbc9c9c1e3ada322021-12-04T16:01:23ZCardiovascular Imaging and Theranostics in Cardiovascular Pharmacotherapy10.15420/ecr.2019.6.11758-37641758-3756https://doaj.org/article/05ae3bd5e640416c8fbc9c9c1e3ada322019-01-01T00:00:00Zhttps://www.ecrjournal.com/articles/cardiovascular-imaging-and-theranostics-cardiovascular-pharmacotherapyhttps://doaj.org/toc/1758-3756https://doaj.org/toc/1758-3764Imaging plays a pivotal role in the diagnostic and prognostic assessment of cardiovascular diseases. During the past two decades, there has been an expansion of the available imaging techniques, some of which are now part of routine clinical practice. Cardiovascular imaging of atherosclerosis is a useful instrument, and it can corroborate and expand pathophysiological evidence on cardiovascular disease, providing proof of concept for medical therapy and can predict its responsiveness, and it may be able to be used as surrogate endpoints for clinical trials. Theranostics is an emerging therapy that combines imaging and therapeutic functions, using imaging-based therapeutic delivery systems. Theranostics could partially overcome current imaging limitations and translate experimental evidence and large-scale trials assessing clinical endpoints, rationalising cardiovascular drug development and paving the way to personalised medicine. The medical community cannot overlook the use of cardiovascular imaging as a complementary and supportive adjunct to trials investigating clinical endpoints, which remain the mainstay for investigating the efficacy and safety of cardiovascular pharmacotherapy.Mattia CattaneoAlberto FroioAugusto GallinoRadcliffe Medical MediaarticleDiseases of the circulatory (Cardiovascular) systemRC666-701ENEuropean Cardiology Review , Vol 14, Iss 1, Pp 62-64 (2019)
institution DOAJ
collection DOAJ
language EN
topic Diseases of the circulatory (Cardiovascular) system
RC666-701
spellingShingle Diseases of the circulatory (Cardiovascular) system
RC666-701
Mattia Cattaneo
Alberto Froio
Augusto Gallino
Cardiovascular Imaging and Theranostics in Cardiovascular Pharmacotherapy
description Imaging plays a pivotal role in the diagnostic and prognostic assessment of cardiovascular diseases. During the past two decades, there has been an expansion of the available imaging techniques, some of which are now part of routine clinical practice. Cardiovascular imaging of atherosclerosis is a useful instrument, and it can corroborate and expand pathophysiological evidence on cardiovascular disease, providing proof of concept for medical therapy and can predict its responsiveness, and it may be able to be used as surrogate endpoints for clinical trials. Theranostics is an emerging therapy that combines imaging and therapeutic functions, using imaging-based therapeutic delivery systems. Theranostics could partially overcome current imaging limitations and translate experimental evidence and large-scale trials assessing clinical endpoints, rationalising cardiovascular drug development and paving the way to personalised medicine. The medical community cannot overlook the use of cardiovascular imaging as a complementary and supportive adjunct to trials investigating clinical endpoints, which remain the mainstay for investigating the efficacy and safety of cardiovascular pharmacotherapy.
format article
author Mattia Cattaneo
Alberto Froio
Augusto Gallino
author_facet Mattia Cattaneo
Alberto Froio
Augusto Gallino
author_sort Mattia Cattaneo
title Cardiovascular Imaging and Theranostics in Cardiovascular Pharmacotherapy
title_short Cardiovascular Imaging and Theranostics in Cardiovascular Pharmacotherapy
title_full Cardiovascular Imaging and Theranostics in Cardiovascular Pharmacotherapy
title_fullStr Cardiovascular Imaging and Theranostics in Cardiovascular Pharmacotherapy
title_full_unstemmed Cardiovascular Imaging and Theranostics in Cardiovascular Pharmacotherapy
title_sort cardiovascular imaging and theranostics in cardiovascular pharmacotherapy
publisher Radcliffe Medical Media
publishDate 2019
url https://doaj.org/article/05ae3bd5e640416c8fbc9c9c1e3ada32
work_keys_str_mv AT mattiacattaneo cardiovascularimagingandtheranosticsincardiovascularpharmacotherapy
AT albertofroio cardiovascularimagingandtheranosticsincardiovascularpharmacotherapy
AT augustogallino cardiovascularimagingandtheranosticsincardiovascularpharmacotherapy
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