Light-inducible antimiR-92a as a therapeutic strategy to promote skin repair in healing-impaired diabetic mice

Inhibition of microRNAs using antimiRs is a potential therapeutic option for a number of diseases, but systemic inhibition may cause adverse effects. Here the authors develop light-activated antimiRs directed against miR-92a, and show localized inhibition in the skin and improved wound healing in di...

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Autores principales:	Tina Lucas, Florian Schäfer, Patricia Müller, Sabine A. Eming, Alexander Heckel, Stefanie Dimmeler
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/05b2c1f634904f4bb3044be5c56fb8dd
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spelling	oai:doaj.org-article:05b2c1f634904f4bb3044be5c56fb8dd2021-12-02T15:38:54ZLight-inducible antimiR-92a as a therapeutic strategy to promote skin repair in healing-impaired diabetic mice10.1038/ncomms151622041-1723https://doaj.org/article/05b2c1f634904f4bb3044be5c56fb8dd2017-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms15162https://doaj.org/toc/2041-1723Inhibition of microRNAs using antimiRs is a potential therapeutic option for a number of diseases, but systemic inhibition may cause adverse effects. Here the authors develop light-activated antimiRs directed against miR-92a, and show localized inhibition in the skin and improved wound healing in diabetic mice.Tina LucasFlorian SchäferPatricia MüllerSabine A. EmingAlexander HeckelStefanie DimmelerNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Tina Lucas Florian Schäfer Patricia Müller Sabine A. Eming Alexander Heckel Stefanie Dimmeler Light-inducible antimiR-92a as a therapeutic strategy to promote skin repair in healing-impaired diabetic mice
description	Inhibition of microRNAs using antimiRs is a potential therapeutic option for a number of diseases, but systemic inhibition may cause adverse effects. Here the authors develop light-activated antimiRs directed against miR-92a, and show localized inhibition in the skin and improved wound healing in diabetic mice.
format	article
author	Tina Lucas Florian Schäfer Patricia Müller Sabine A. Eming Alexander Heckel Stefanie Dimmeler
author_facet	Tina Lucas Florian Schäfer Patricia Müller Sabine A. Eming Alexander Heckel Stefanie Dimmeler
author_sort	Tina Lucas
title	Light-inducible antimiR-92a as a therapeutic strategy to promote skin repair in healing-impaired diabetic mice
title_short	Light-inducible antimiR-92a as a therapeutic strategy to promote skin repair in healing-impaired diabetic mice
title_full	Light-inducible antimiR-92a as a therapeutic strategy to promote skin repair in healing-impaired diabetic mice
title_fullStr	Light-inducible antimiR-92a as a therapeutic strategy to promote skin repair in healing-impaired diabetic mice
title_full_unstemmed	Light-inducible antimiR-92a as a therapeutic strategy to promote skin repair in healing-impaired diabetic mice
title_sort	light-inducible antimir-92a as a therapeutic strategy to promote skin repair in healing-impaired diabetic mice
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/05b2c1f634904f4bb3044be5c56fb8dd
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Light-inducible antimiR-92a as a therapeutic strategy to promote skin repair in healing-impaired diabetic mice

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