Pressure modulates the self-cleavage step of the hairpin ribozyme

Studying the reactivity of ribozymes under extreme pressure could provide insights to optimize biocatalytic RNA design. Here, the authors show that at high pressure the transesterification step of the hairpin ribozyme self-cleavage reaction accelerates, while the overall process is slower.

Guardado en:

Detalles Bibliográficos
Autores principales:	Caroline Schuabb, Narendra Kumar, Salome Pataraia, Dominik Marx, Roland Winter
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/05b58b73a1014bc7b73aa2c2168b3b62
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:05b58b73a1014bc7b73aa2c2168b3b62
record_format	dspace
spelling	oai:doaj.org-article:05b58b73a1014bc7b73aa2c2168b3b622021-12-02T15:38:55ZPressure modulates the self-cleavage step of the hairpin ribozyme10.1038/ncomms146612041-1723https://doaj.org/article/05b58b73a1014bc7b73aa2c2168b3b622017-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms14661https://doaj.org/toc/2041-1723Studying the reactivity of ribozymes under extreme pressure could provide insights to optimize biocatalytic RNA design. Here, the authors show that at high pressure the transesterification step of the hairpin ribozyme self-cleavage reaction accelerates, while the overall process is slower.Caroline SchuabbNarendra KumarSalome PataraiaDominik MarxRoland WinterNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Caroline Schuabb Narendra Kumar Salome Pataraia Dominik Marx Roland Winter Pressure modulates the self-cleavage step of the hairpin ribozyme
description	Studying the reactivity of ribozymes under extreme pressure could provide insights to optimize biocatalytic RNA design. Here, the authors show that at high pressure the transesterification step of the hairpin ribozyme self-cleavage reaction accelerates, while the overall process is slower.
format	article
author	Caroline Schuabb Narendra Kumar Salome Pataraia Dominik Marx Roland Winter
author_facet	Caroline Schuabb Narendra Kumar Salome Pataraia Dominik Marx Roland Winter
author_sort	Caroline Schuabb
title	Pressure modulates the self-cleavage step of the hairpin ribozyme
title_short	Pressure modulates the self-cleavage step of the hairpin ribozyme
title_full	Pressure modulates the self-cleavage step of the hairpin ribozyme
title_fullStr	Pressure modulates the self-cleavage step of the hairpin ribozyme
title_full_unstemmed	Pressure modulates the self-cleavage step of the hairpin ribozyme
title_sort	pressure modulates the self-cleavage step of the hairpin ribozyme
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/05b58b73a1014bc7b73aa2c2168b3b62
work_keys_str_mv	AT carolineschuabb pressuremodulatestheselfcleavagestepofthehairpinribozyme AT narendrakumar pressuremodulatestheselfcleavagestepofthehairpinribozyme AT salomepataraia pressuremodulatestheselfcleavagestepofthehairpinribozyme AT dominikmarx pressuremodulatestheselfcleavagestepofthehairpinribozyme AT rolandwinter pressuremodulatestheselfcleavagestepofthehairpinribozyme
_version_	1718386031493906432

Pressure modulates the self-cleavage step of the hairpin ribozyme

Ejemplares similares