Mobilization of endothelial progenitor cells after endovascular interventions in patients with type 2 diabetes mellitus
Aim. To investigate the mobilisation of endothelial progenitor cells (EPC) in patients with type 2 diabetes mellitus (T2DM) after endovascular interventions for coronary and peripheral arteries. Materials and Methods. The levels of EPC in peripheral blood were determined by flow cytometry in 42 pa...
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Endocrinology Research Centre
2014
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oai:doaj.org-article:05bdf0ee468b4b8bac3405aa538fed322021-11-14T09:00:19ZMobilization of endothelial progenitor cells after endovascular interventions in patients with type 2 diabetes mellitus2072-03512072-037810.14341/DM2014435-42https://doaj.org/article/05bdf0ee468b4b8bac3405aa538fed322014-12-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/6819https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378Aim. To investigate the mobilisation of endothelial progenitor cells (EPC) in patients with type 2 diabetes mellitus (T2DM) after endovascular interventions for coronary and peripheral arteries. Materials and Methods. The levels of EPC in peripheral blood were determined by flow cytometry in 42 patients prior to endovascular intervention and 2?4 days after surgery. EPC were defined as CD34+ VEGFR2+ CD45- and CD34+ CD133+CD45- cells. Twenty-three patients with T2DM were included in group 1, and 19 patients without metabolic disorders were included in group 2. Results. The levels of EPC in the peripheral blood of patients with T2DM before and after endovascular interventions were not significantly different. In the subgroup of patients without TDM2, the levels of CD34+VEGFR2 +CD45- cells increased after surgery to 55,5% (pMarina Sergeevna MichurovaVictor Yur'evich KalashnikovOlga Michailovna SmirnovaOlga Nikolaevna IvanovaSergey Anatol'evich TerekhinEndocrinology Research Centrearticlediabetes mellitusendothelial progenitor cellsmobilisationpercutaneous coronary interventionlower extremity revascularizationNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 17, Iss 4, Pp 35-42 (2014) |
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DOAJ |
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EN RU |
| topic |
diabetes mellitus endothelial progenitor cells mobilisation percutaneous coronary intervention lower extremity revascularization Nutritional diseases. Deficiency diseases RC620-627 |
| spellingShingle |
diabetes mellitus endothelial progenitor cells mobilisation percutaneous coronary intervention lower extremity revascularization Nutritional diseases. Deficiency diseases RC620-627 Marina Sergeevna Michurova Victor Yur'evich Kalashnikov Olga Michailovna Smirnova Olga Nikolaevna Ivanova Sergey Anatol'evich Terekhin Mobilization of endothelial progenitor cells after endovascular interventions in patients with type 2 diabetes mellitus |
| description |
Aim. To investigate the mobilisation of endothelial progenitor cells (EPC) in patients with type 2 diabetes mellitus (T2DM) after endovascular interventions for coronary and peripheral arteries. Materials and Methods. The levels of EPC in peripheral blood were determined by flow cytometry in 42 patients prior to endovascular intervention and 2?4 days after surgery. EPC were defined as CD34+ VEGFR2+ CD45- and CD34+ CD133+CD45- cells. Twenty-three patients with T2DM were included in group 1, and 19 patients without metabolic disorders were included in group 2. Results. The levels of EPC in the peripheral blood of patients with T2DM before and after endovascular interventions were not significantly different. In the subgroup of patients without TDM2, the levels of CD34+VEGFR2 +CD45- cells increased after surgery to 55,5% (p |
| format |
article |
| author |
Marina Sergeevna Michurova Victor Yur'evich Kalashnikov Olga Michailovna Smirnova Olga Nikolaevna Ivanova Sergey Anatol'evich Terekhin |
| author_facet |
Marina Sergeevna Michurova Victor Yur'evich Kalashnikov Olga Michailovna Smirnova Olga Nikolaevna Ivanova Sergey Anatol'evich Terekhin |
| author_sort |
Marina Sergeevna Michurova |
| title |
Mobilization of endothelial progenitor cells after endovascular interventions in patients with type 2 diabetes mellitus |
| title_short |
Mobilization of endothelial progenitor cells after endovascular interventions in patients with type 2 diabetes mellitus |
| title_full |
Mobilization of endothelial progenitor cells after endovascular interventions in patients with type 2 diabetes mellitus |
| title_fullStr |
Mobilization of endothelial progenitor cells after endovascular interventions in patients with type 2 diabetes mellitus |
| title_full_unstemmed |
Mobilization of endothelial progenitor cells after endovascular interventions in patients with type 2 diabetes mellitus |
| title_sort |
mobilization of endothelial progenitor cells after endovascular interventions in patients with type 2 diabetes mellitus |
| publisher |
Endocrinology Research Centre |
| publishDate |
2014 |
| url |
https://doaj.org/article/05bdf0ee468b4b8bac3405aa538fed32 |
| work_keys_str_mv |
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| _version_ |
1718429506739372032 |