ASSOCIATION OF ANEMIA WITH SERUM SEX HORMONE BINDING GLOBULIN LEVELS IN PATIENTS WITH POLYCYSTIC OVARY SYNDROME

Objective: To find association of anemia with serum sex hormone binding globulin levels in women with PCOS. Study Design: Cross sectional study. Place and Duration of Study: University of Health Sciences Lahore, from Jan 2018 to Jun 2018. Methodology: The study was conducted after approval...

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Autores principales:	Hafiza Swaiba Afzal, Syeda Rizwana Jafri, Amna Muneeb, Attya Zaheer, Ehsan Ahmad, Bushra Batool
Formato:	article
Lenguaje:	EN
Publicado:	Army Medical College Rawalpindi 2020
Materias:	anemia polycystic ovary syndrome Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/05c132d2401f4ac181d1ec7254d0bbea
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spelling	oai:doaj.org-article:05c132d2401f4ac181d1ec7254d0bbea2021-11-05T02:43:32ZASSOCIATION OF ANEMIA WITH SERUM SEX HORMONE BINDING GLOBULIN LEVELS IN PATIENTS WITH POLYCYSTIC OVARY SYNDROME0030-96482411-8842https://doaj.org/article/05c132d2401f4ac181d1ec7254d0bbea2020-12-01T00:00:00Zhttps://www.pafmj.org/index.php/PAFMJ/article/view/5881/3078https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To find association of anemia with serum sex hormone binding globulin levels in women with PCOS. Study Design: Cross sectional study. Place and Duration of Study: University of Health Sciences Lahore, from Jan 2018 to Jun 2018. Methodology: The study was conducted after approval from Ethics review committee of University of Health Sciences, Lahore. The Data was assessed by IBM-SPSS version 22. Normality of different continuous variables was checked by Shapiro-wilk test. Frequency distributions of study participants were calculated. Significance of the associations was assessed by Mann Whitney-U test and p-value <0.05 was taken as statistically significant. Results: Most of the participants of our study were married (53.3%) and 77.9% of these married women don’t have children. 35 out of 60 were anemic (58.3%). The median ± interquartile ranges of age, BMI, SHBG and serum testosterone were 25 ± 9, 25.5 ± 9.75, 22.2 ± 13.08 and 0.24 ± 0.15 respectively. Mean Serum sex hormone binding globulin levels were found to be significantly associated with anemia (P=0.046) with mean ± SD of 16.30 ± 5.61 in anemic patients which was lower than the normal blood levels of SHBG (18-140 nmol/l). Anemia was nonsignificantly associated with the other factors like age, BMI and serum testosterone. Conclusions: It was evident from this study that anemia is strongly associated with SHBG levels in PCOS. Further studies are required with larger sample size in future to rule out the underlying causes.Hafiza Swaiba AfzalSyeda Rizwana JafriAmna MuneebAttya ZaheerEhsan AhmadBushra BatoolArmy Medical College Rawalpindiarticleanemiapolycystic ovary syndromeMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 70, Iss 6, Pp 1870-1873 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	anemia polycystic ovary syndrome Medicine R Medicine (General) R5-920
spellingShingle	anemia polycystic ovary syndrome Medicine R Medicine (General) R5-920 Hafiza Swaiba Afzal Syeda Rizwana Jafri Amna Muneeb Attya Zaheer Ehsan Ahmad Bushra Batool ASSOCIATION OF ANEMIA WITH SERUM SEX HORMONE BINDING GLOBULIN LEVELS IN PATIENTS WITH POLYCYSTIC OVARY SYNDROME
description	Objective: To find association of anemia with serum sex hormone binding globulin levels in women with PCOS. Study Design: Cross sectional study. Place and Duration of Study: University of Health Sciences Lahore, from Jan 2018 to Jun 2018. Methodology: The study was conducted after approval from Ethics review committee of University of Health Sciences, Lahore. The Data was assessed by IBM-SPSS version 22. Normality of different continuous variables was checked by Shapiro-wilk test. Frequency distributions of study participants were calculated. Significance of the associations was assessed by Mann Whitney-U test and p-value <0.05 was taken as statistically significant. Results: Most of the participants of our study were married (53.3%) and 77.9% of these married women don’t have children. 35 out of 60 were anemic (58.3%). The median ± interquartile ranges of age, BMI, SHBG and serum testosterone were 25 ± 9, 25.5 ± 9.75, 22.2 ± 13.08 and 0.24 ± 0.15 respectively. Mean Serum sex hormone binding globulin levels were found to be significantly associated with anemia (P=0.046) with mean ± SD of 16.30 ± 5.61 in anemic patients which was lower than the normal blood levels of SHBG (18-140 nmol/l). Anemia was nonsignificantly associated with the other factors like age, BMI and serum testosterone. Conclusions: It was evident from this study that anemia is strongly associated with SHBG levels in PCOS. Further studies are required with larger sample size in future to rule out the underlying causes.
format	article
author	Hafiza Swaiba Afzal Syeda Rizwana Jafri Amna Muneeb Attya Zaheer Ehsan Ahmad Bushra Batool
author_facet	Hafiza Swaiba Afzal Syeda Rizwana Jafri Amna Muneeb Attya Zaheer Ehsan Ahmad Bushra Batool
author_sort	Hafiza Swaiba Afzal
title	ASSOCIATION OF ANEMIA WITH SERUM SEX HORMONE BINDING GLOBULIN LEVELS IN PATIENTS WITH POLYCYSTIC OVARY SYNDROME
title_short	ASSOCIATION OF ANEMIA WITH SERUM SEX HORMONE BINDING GLOBULIN LEVELS IN PATIENTS WITH POLYCYSTIC OVARY SYNDROME
title_full	ASSOCIATION OF ANEMIA WITH SERUM SEX HORMONE BINDING GLOBULIN LEVELS IN PATIENTS WITH POLYCYSTIC OVARY SYNDROME
title_fullStr	ASSOCIATION OF ANEMIA WITH SERUM SEX HORMONE BINDING GLOBULIN LEVELS IN PATIENTS WITH POLYCYSTIC OVARY SYNDROME
title_full_unstemmed	ASSOCIATION OF ANEMIA WITH SERUM SEX HORMONE BINDING GLOBULIN LEVELS IN PATIENTS WITH POLYCYSTIC OVARY SYNDROME
title_sort	association of anemia with serum sex hormone binding globulin levels in patients with polycystic ovary syndrome
publisher	Army Medical College Rawalpindi
publishDate	2020
url	https://doaj.org/article/05c132d2401f4ac181d1ec7254d0bbea
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ASSOCIATION OF ANEMIA WITH SERUM SEX HORMONE BINDING GLOBULIN LEVELS IN PATIENTS WITH POLYCYSTIC OVARY SYNDROME

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