Comparing the Effects of Propofol Infusion and Inhalation Isoflurane on Hemodynamic Variations and Depth of Anesthesia in Cataract Surgery Patients

BACKGROUND AND OBJECTIVE: In cataract surgery, given that most patients are older people, surgery with general anesthesia requires better hemodynamic control along with maintaining the depth of anesthesia. The present study was conducted to compare the effects of propofol and isoflurane on hemodynam...

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Autores principales:	M khakzad, M Rabiee, E Alijanpour, N Banihashem, M ghasemi jirdehi, S Khafri
Formato:	article
Lenguaje:	EN FA
Publicado:	Babol University of Medical Sciences 2019
Materias:	cataract depth of anesthesia hemodynamic variations propofol isoflurane Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/05c4f297f02c4f579422e87133e6f273
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spelling	oai:doaj.org-article:05c4f297f02c4f579422e87133e6f2732021-11-10T08:30:37ZComparing the Effects of Propofol Infusion and Inhalation Isoflurane on Hemodynamic Variations and Depth of Anesthesia in Cataract Surgery Patients1561-41072251-7170https://doaj.org/article/05c4f297f02c4f579422e87133e6f2732019-12-01T00:00:00Zhttp://jbums.org/article-1-8641-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170BACKGROUND AND OBJECTIVE: In cataract surgery, given that most patients are older people, surgery with general anesthesia requires better hemodynamic control along with maintaining the depth of anesthesia. The present study was conducted to compare the effects of propofol and isoflurane on hemodynamic variations and depth of anesthesia in cataract surgery patients. METHODS: The present clinical trial was conducted among 60 patients who were cataract surgery candidates. The patients were randomly assigned to propofol group (n = 30) and isoflurane group (n = 30). One µg/kg fentanyl and one mg/kg intravenous lidocaine were administered in both groups and anesthesia was induced using 1.5 – 2.5 mg/kg propofol. In order to maintain anesthesia, 50 – 75 µg/kg/min propofol was administered in the first group and 1% isoflurane was administered in the second group. Depth of anesthesia, hemodynamic variations, recovery time, wake-up time, nausea and vomiting were recorded and compared in the two groups. FINDINGS: Depth of anesthesia was similarly below 60 in both groups at different times. Hemodynamic variations were not significantly different in the two groups. Mean recovery time in propofol and isoflurane groups was 20.56 and 15.4 minutes, respectively (p<0.001), and wake-up time in the two groups was 8.83 and 7.16 minutes, respectively (p= 0.004). CONCLUSION: The results showed that there was no difference between the effects of these two drugs on hemodynamics and depth of anesthesia, but recovery time and wake-up time in propofol group were significantly higher than isoflurane group.M khakzadM RabieeE AlijanpourN BanihashemM ghasemi jirdehiS KhafriM khakzadBabol University of Medical Sciencesarticlecataractdepth of anesthesiahemodynamic variationspropofolisofluraneMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 21, Iss 1, Pp 398-402 (2019)
institution	DOAJ
collection	DOAJ
language	EN FA
topic	cataract depth of anesthesia hemodynamic variations propofol isoflurane Medicine R Medicine (General) R5-920
spellingShingle	cataract depth of anesthesia hemodynamic variations propofol isoflurane Medicine R Medicine (General) R5-920 M khakzad M Rabiee E Alijanpour N Banihashem M ghasemi jirdehi S Khafri M khakzad Comparing the Effects of Propofol Infusion and Inhalation Isoflurane on Hemodynamic Variations and Depth of Anesthesia in Cataract Surgery Patients
description	BACKGROUND AND OBJECTIVE: In cataract surgery, given that most patients are older people, surgery with general anesthesia requires better hemodynamic control along with maintaining the depth of anesthesia. The present study was conducted to compare the effects of propofol and isoflurane on hemodynamic variations and depth of anesthesia in cataract surgery patients. METHODS: The present clinical trial was conducted among 60 patients who were cataract surgery candidates. The patients were randomly assigned to propofol group (n = 30) and isoflurane group (n = 30). One µg/kg fentanyl and one mg/kg intravenous lidocaine were administered in both groups and anesthesia was induced using 1.5 – 2.5 mg/kg propofol. In order to maintain anesthesia, 50 – 75 µg/kg/min propofol was administered in the first group and 1% isoflurane was administered in the second group. Depth of anesthesia, hemodynamic variations, recovery time, wake-up time, nausea and vomiting were recorded and compared in the two groups. FINDINGS: Depth of anesthesia was similarly below 60 in both groups at different times. Hemodynamic variations were not significantly different in the two groups. Mean recovery time in propofol and isoflurane groups was 20.56 and 15.4 minutes, respectively (p<0.001), and wake-up time in the two groups was 8.83 and 7.16 minutes, respectively (p= 0.004). CONCLUSION: The results showed that there was no difference between the effects of these two drugs on hemodynamics and depth of anesthesia, but recovery time and wake-up time in propofol group were significantly higher than isoflurane group.
format	article
author	M khakzad M Rabiee E Alijanpour N Banihashem M ghasemi jirdehi S Khafri M khakzad
author_facet	M khakzad M Rabiee E Alijanpour N Banihashem M ghasemi jirdehi S Khafri M khakzad
author_sort	M khakzad
title	Comparing the Effects of Propofol Infusion and Inhalation Isoflurane on Hemodynamic Variations and Depth of Anesthesia in Cataract Surgery Patients
title_short	Comparing the Effects of Propofol Infusion and Inhalation Isoflurane on Hemodynamic Variations and Depth of Anesthesia in Cataract Surgery Patients
title_full	Comparing the Effects of Propofol Infusion and Inhalation Isoflurane on Hemodynamic Variations and Depth of Anesthesia in Cataract Surgery Patients
title_fullStr	Comparing the Effects of Propofol Infusion and Inhalation Isoflurane on Hemodynamic Variations and Depth of Anesthesia in Cataract Surgery Patients
title_full_unstemmed	Comparing the Effects of Propofol Infusion and Inhalation Isoflurane on Hemodynamic Variations and Depth of Anesthesia in Cataract Surgery Patients
title_sort	comparing the effects of propofol infusion and inhalation isoflurane on hemodynamic variations and depth of anesthesia in cataract surgery patients
publisher	Babol University of Medical Sciences
publishDate	2019
url	https://doaj.org/article/05c4f297f02c4f579422e87133e6f273
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Comparing the Effects of Propofol Infusion and Inhalation Isoflurane on Hemodynamic Variations and Depth of Anesthesia in Cataract Surgery Patients

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