H3K9me3-mediated epigenetic regulation of senescence in mice predicts outcome of lymphoma patients

Therapy-induced senescence reflects a biological effector principle that is underrecognized in lesion-focused cancer precision medicine. Here the authors utilize mouse lymphoma genetics to functionally dissect senescence and cross-species apply a novel senescence-based prognosticator to lymphoma pat...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Kolja Schleich, Julia Kase, Jan R. Dörr, Saskia Trescher, Animesh Bhattacharya, Yong Yu, Elizabeth M. Wailes, Dorothy N. Y. Fan, Philipp Lohneis, Maja Milanovic, Andrea Lau, Dido Lenze, Michael Hummel, Bjoern Chapuy, Ulf Leser, Maurice Reimann, Soyoung Lee, Clemens A. Schmitt
Format: article
Langue:EN
Publié: Nature Portfolio 2020
Sujets:
Q
Accès en ligne:https://doaj.org/article/05c76f30d3fb41ad9a1c454ca0327848
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!