Emerging roles of eraser enzymes in the dynamic control of protein ADP-ribosylation

ADP-ribose erasing enzymes are increasingly recognized as critical regulators of protein ADP-ribosylation dynamics in living systems. Here, the authors review recent advances in the discovery and characterization of ADP-ribose erasers and discuss their role within the cellular ADP-ribosylation machi...

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Autores principales: Julia O’Sullivan, Maria Tedim Ferreira, Jean-Philippe Gagné, Ajit K. Sharma, Michael J. Hendzel, Jean-Yves Masson, Guy G. Poirier
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/05d8f39e0141460487e8fe00b0a3d6e4
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spelling oai:doaj.org-article:05d8f39e0141460487e8fe00b0a3d6e42021-12-02T17:32:09ZEmerging roles of eraser enzymes in the dynamic control of protein ADP-ribosylation10.1038/s41467-019-08859-x2041-1723https://doaj.org/article/05d8f39e0141460487e8fe00b0a3d6e42019-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08859-xhttps://doaj.org/toc/2041-1723ADP-ribose erasing enzymes are increasingly recognized as critical regulators of protein ADP-ribosylation dynamics in living systems. Here, the authors review recent advances in the discovery and characterization of ADP-ribose erasers and discuss their role within the cellular ADP-ribosylation machinery.Julia O’SullivanMaria Tedim FerreiraJean-Philippe GagnéAjit K. SharmaMichael J. HendzelJean-Yves MassonGuy G. PoirierNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Julia O’Sullivan
Maria Tedim Ferreira
Jean-Philippe Gagné
Ajit K. Sharma
Michael J. Hendzel
Jean-Yves Masson
Guy G. Poirier
Emerging roles of eraser enzymes in the dynamic control of protein ADP-ribosylation
description ADP-ribose erasing enzymes are increasingly recognized as critical regulators of protein ADP-ribosylation dynamics in living systems. Here, the authors review recent advances in the discovery and characterization of ADP-ribose erasers and discuss their role within the cellular ADP-ribosylation machinery.
format article
author Julia O’Sullivan
Maria Tedim Ferreira
Jean-Philippe Gagné
Ajit K. Sharma
Michael J. Hendzel
Jean-Yves Masson
Guy G. Poirier
author_facet Julia O’Sullivan
Maria Tedim Ferreira
Jean-Philippe Gagné
Ajit K. Sharma
Michael J. Hendzel
Jean-Yves Masson
Guy G. Poirier
author_sort Julia O’Sullivan
title Emerging roles of eraser enzymes in the dynamic control of protein ADP-ribosylation
title_short Emerging roles of eraser enzymes in the dynamic control of protein ADP-ribosylation
title_full Emerging roles of eraser enzymes in the dynamic control of protein ADP-ribosylation
title_fullStr Emerging roles of eraser enzymes in the dynamic control of protein ADP-ribosylation
title_full_unstemmed Emerging roles of eraser enzymes in the dynamic control of protein ADP-ribosylation
title_sort emerging roles of eraser enzymes in the dynamic control of protein adp-ribosylation
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/05d8f39e0141460487e8fe00b0a3d6e4
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