Metformin and cancer mortality

The author analyses recent publications supporting the ability of metformin to decrease the risk of cancer morbidity and mortality in patients with type 2diabetes mellitus. Pre-history of the problem (including the use of biguanides for metabolic rehabilitation of oncological patients), the role of...

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Autor principal: Lev Mikhaylovich Bershteyn
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RU
Publicado: Endocrinology Research Centre 2010
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Acceso en línea:https://doaj.org/article/05da729af1a04fbb8decb7c01a66bd6a
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spelling oai:doaj.org-article:05da729af1a04fbb8decb7c01a66bd6a2021-11-14T09:00:15ZMetformin and cancer mortality2072-03512072-037810.14341/2072-0351-5491https://doaj.org/article/05da729af1a04fbb8decb7c01a66bd6a2010-09-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/5491https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378The author analyses recent publications supporting the ability of metformin to decrease the risk of cancer morbidity and mortality in patients with type 2diabetes mellitus. Pre-history of the problem (including the use of biguanides for metabolic rehabilitation of oncological patients), the role of DM as a riskfactor of cancer morbidity and mortality, mechanisms and targets of metformin anticancer effects, and potential use of this agent in non-diabetic patientsare discussed. The need for the search of the markers of sensitivity and resistance to metformin to be used in oncological practice is emphasized.Lev Mikhaylovich BershteynEndocrinology Research Centrearticlemetformindiabetes mellitusoncological diseasesNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 13, Iss 3, Pp 66-70 (2010)
institution DOAJ
collection DOAJ
language EN
RU
topic metformin
diabetes mellitus
oncological diseases
Nutritional diseases. Deficiency diseases
RC620-627
spellingShingle metformin
diabetes mellitus
oncological diseases
Nutritional diseases. Deficiency diseases
RC620-627
Lev Mikhaylovich Bershteyn
Metformin and cancer mortality
description The author analyses recent publications supporting the ability of metformin to decrease the risk of cancer morbidity and mortality in patients with type 2diabetes mellitus. Pre-history of the problem (including the use of biguanides for metabolic rehabilitation of oncological patients), the role of DM as a riskfactor of cancer morbidity and mortality, mechanisms and targets of metformin anticancer effects, and potential use of this agent in non-diabetic patientsare discussed. The need for the search of the markers of sensitivity and resistance to metformin to be used in oncological practice is emphasized.
format article
author Lev Mikhaylovich Bershteyn
author_facet Lev Mikhaylovich Bershteyn
author_sort Lev Mikhaylovich Bershteyn
title Metformin and cancer mortality
title_short Metformin and cancer mortality
title_full Metformin and cancer mortality
title_fullStr Metformin and cancer mortality
title_full_unstemmed Metformin and cancer mortality
title_sort metformin and cancer mortality
publisher Endocrinology Research Centre
publishDate 2010
url https://doaj.org/article/05da729af1a04fbb8decb7c01a66bd6a
work_keys_str_mv AT levmikhaylovichbershteyn metforminandcancermortality
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