Antibiotic resistance profiling of Uropathogenic Enterobacteriaceae, Casablanca, Morocco

Introduction: the urinary tract infection is a pathology frequents as well in community as at the hospital. In last years, there has been increased the incidence of antibiotic resistance in Uropathogenic Enterobacteriaceae. This development explains the need for periodic regional surveillance of thi...

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Autores principales:	Rafik Aniba, Abouddihaj Barguigua, Asmaa Dihmane, Kaotar Nayme, Mohammed Timinouni
Formato:	article
Lenguaje:	EN FR
Publicado:	EDP Sciences 2021
Materias:	urinary tract infection cytobacteriological urine examination (ecbu) enterobacteriaceae antibiogram antibiotic resistance Environmental sciences GE1-350
Acceso en línea:	https://doaj.org/article/05e258f5d19b4da5bb2e304968a1a3c8
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spelling	oai:doaj.org-article:05e258f5d19b4da5bb2e304968a1a3c82021-11-12T11:44:07ZAntibiotic resistance profiling of Uropathogenic Enterobacteriaceae, Casablanca, Morocco2267-124210.1051/e3sconf/202131901002https://doaj.org/article/05e258f5d19b4da5bb2e304968a1a3c82021-01-01T00:00:00Zhttps://www.e3s-conferences.org/articles/e3sconf/pdf/2021/95/e3sconf_vigisan_01002.pdfhttps://doaj.org/toc/2267-1242Introduction: the urinary tract infection is a pathology frequents as well in community as at the hospital. In last years, there has been increased the incidence of antibiotic resistance in Uropathogenic Enterobacteriaceae. This development explains the need for periodic regional surveillance of this resistance to antibiotics, which poses a real problem of public health, because it affects several molecules ranging from β-lactam to quinolones. Objective: the aims of this study is to determine the profile of antibiotic resistance of Uropathogenic Enterobacteriaceae isolated from medical analysis laboratories in Casablanca, Morocco. Materials and methods: This is a prospective study that was conducted on patients who visited medical analysis laboratories in Casablanca city, for urinalysis test from 01 January 2017 to 30 December 2018 (a two full years). The culture was performed according to the usual techniques, and the antibiogram was done according to the recommendations of the Antibiogram Committee of the French Society of Microbiology. The statistical analysis was performed using Microsoft Excel (Microsoft 2016). Results: During our study, we reported 18% of urinary tract infections, Sex ratio F/M was 1.79. In addition, Enterobacteriaceae were the most common germs. Of all the strains isolated, we noted a predominance of Escherichia coli with 75.41%) and Klebsiella ssp with 17.05%. In the course of this study period, we observed high rates of resistance to the main classes of antibiotics, and an overall increase between 2017 and 2018 in this resistance to the majority of β-lactam antibiotics, quinolones and aminoglycosides for almost all species of Uropathogenic Enterobacteriaceae. However, amikacin was the most active molecule against the Uropathogenic Enterobacteriaceae strains isolates. Conclusion: The development of resistance of Uropathogenic Enterobacteriaceae to antibiotics is a worrying phenomenon that exposes us to difficulties in the therapeutic management of infections. The current control of antimicrobial resistance is a real emergency and requires the involvement of public awareness before government instructions.Rafik AnibaAbouddihaj BarguiguaAsmaa DihmaneKaotar NaymeMohammed TiminouniEDP Sciencesarticleurinary tract infectioncytobacteriological urine examination (ecbu)enterobacteriaceaeantibiogramantibiotic resistanceEnvironmental sciencesGE1-350ENFRE3S Web of Conferences, Vol 319, p 01002 (2021)
institution	DOAJ
collection	DOAJ
language	EN FR
topic	urinary tract infection cytobacteriological urine examination (ecbu) enterobacteriaceae antibiogram antibiotic resistance Environmental sciences GE1-350
spellingShingle	urinary tract infection cytobacteriological urine examination (ecbu) enterobacteriaceae antibiogram antibiotic resistance Environmental sciences GE1-350 Rafik Aniba Abouddihaj Barguigua Asmaa Dihmane Kaotar Nayme Mohammed Timinouni Antibiotic resistance profiling of Uropathogenic Enterobacteriaceae, Casablanca, Morocco
description	Introduction: the urinary tract infection is a pathology frequents as well in community as at the hospital. In last years, there has been increased the incidence of antibiotic resistance in Uropathogenic Enterobacteriaceae. This development explains the need for periodic regional surveillance of this resistance to antibiotics, which poses a real problem of public health, because it affects several molecules ranging from β-lactam to quinolones. Objective: the aims of this study is to determine the profile of antibiotic resistance of Uropathogenic Enterobacteriaceae isolated from medical analysis laboratories in Casablanca, Morocco. Materials and methods: This is a prospective study that was conducted on patients who visited medical analysis laboratories in Casablanca city, for urinalysis test from 01 January 2017 to 30 December 2018 (a two full years). The culture was performed according to the usual techniques, and the antibiogram was done according to the recommendations of the Antibiogram Committee of the French Society of Microbiology. The statistical analysis was performed using Microsoft Excel (Microsoft 2016). Results: During our study, we reported 18% of urinary tract infections, Sex ratio F/M was 1.79. In addition, Enterobacteriaceae were the most common germs. Of all the strains isolated, we noted a predominance of Escherichia coli with 75.41%) and Klebsiella ssp with 17.05%. In the course of this study period, we observed high rates of resistance to the main classes of antibiotics, and an overall increase between 2017 and 2018 in this resistance to the majority of β-lactam antibiotics, quinolones and aminoglycosides for almost all species of Uropathogenic Enterobacteriaceae. However, amikacin was the most active molecule against the Uropathogenic Enterobacteriaceae strains isolates. Conclusion: The development of resistance of Uropathogenic Enterobacteriaceae to antibiotics is a worrying phenomenon that exposes us to difficulties in the therapeutic management of infections. The current control of antimicrobial resistance is a real emergency and requires the involvement of public awareness before government instructions.
format	article
author	Rafik Aniba Abouddihaj Barguigua Asmaa Dihmane Kaotar Nayme Mohammed Timinouni
author_facet	Rafik Aniba Abouddihaj Barguigua Asmaa Dihmane Kaotar Nayme Mohammed Timinouni
author_sort	Rafik Aniba
title	Antibiotic resistance profiling of Uropathogenic Enterobacteriaceae, Casablanca, Morocco
title_short	Antibiotic resistance profiling of Uropathogenic Enterobacteriaceae, Casablanca, Morocco
title_full	Antibiotic resistance profiling of Uropathogenic Enterobacteriaceae, Casablanca, Morocco
title_fullStr	Antibiotic resistance profiling of Uropathogenic Enterobacteriaceae, Casablanca, Morocco
title_full_unstemmed	Antibiotic resistance profiling of Uropathogenic Enterobacteriaceae, Casablanca, Morocco
title_sort	antibiotic resistance profiling of uropathogenic enterobacteriaceae, casablanca, morocco
publisher	EDP Sciences
publishDate	2021
url	https://doaj.org/article/05e258f5d19b4da5bb2e304968a1a3c8
work_keys_str_mv	AT rafikaniba antibioticresistanceprofilingofuropathogenicenterobacteriaceaecasablancamorocco AT abouddihajbarguigua antibioticresistanceprofilingofuropathogenicenterobacteriaceaecasablancamorocco AT asmaadihmane antibioticresistanceprofilingofuropathogenicenterobacteriaceaecasablancamorocco AT kaotarnayme antibioticresistanceprofilingofuropathogenicenterobacteriaceaecasablancamorocco AT mohammedtiminouni antibioticresistanceprofilingofuropathogenicenterobacteriaceaecasablancamorocco
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Antibiotic resistance profiling of Uropathogenic Enterobacteriaceae, Casablanca, Morocco

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