The Instant and Sustained Effect of Electroacupuncture in Postgraduate Students with Depression: An fMRI Study

Xiang-yu Wei, Hui Chen, Cui Guo, Wen-li Tan, Song-hua Zhan Department of Radiology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, People’s Republic of ChinaCorrespondence: Song-hua Zhan; Hui ChenDepartment of Radiology, Shuguang Hosp...

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Autores principales:	Wei X, Chen H, Guo C, Tan W, Zhan S
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2021
Materias:	acupuncture functional magnetic resonance imaging depression default mode network neuroimaging Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/05edc9baca694d7282e82bf761e0bea7
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spelling	oai:doaj.org-article:05edc9baca694d7282e82bf761e0bea72021-12-02T11:39:22ZThe Instant and Sustained Effect of Electroacupuncture in Postgraduate Students with Depression: An fMRI Study1178-2021https://doaj.org/article/05edc9baca694d7282e82bf761e0bea72021-03-01T00:00:00Zhttps://www.dovepress.com/the-instant-and-sustained-effect-of-electroacupuncture-in-postgraduate-peer-reviewed-article-NDThttps://doaj.org/toc/1178-2021Xiang-yu Wei, Hui Chen, Cui Guo, Wen-li Tan, Song-hua Zhan Department of Radiology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, People’s Republic of ChinaCorrespondence: Song-hua Zhan; Hui ChenDepartment of Radiology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, 528 Zhangheng Road, Pudong New Area, Shanghai, 201203, People’s Republic of ChinaEmail zhansonghua@sina.com; chenhui660245@163.comObjection: This study was a primary study to evaluate the instant and sustained effect of electroacupuncture (EA) at GV20 (Baihui) in postgraduate students with mild depression by using a special flexible head coil.Methods: A total of 20 postgraduate students with mild depression underwent EA stimulation at GV20 and 3 phases of resting-state functional magnetic resonance imaging (rs-fMRI) scanning. Phase I: Preparation (before needle insertion); Phase II: during EA; Phase III: 15 minutes after needle removal. The Rs-fMRI data were processed using DPABI and SPSS 25.Results: 1) ReHo values showed significantly differences in the right posterior cingulate cortex, right calcarine gyrus, right angular gyrus, right precuneus, right cuneus, and bilateral postcentral gyri among Phase I, Phase II and Phase III; 2) Relative to the Phase I, increased brain activity in the Phase II was observed in the bilateral postcentral gyri, right calcarine gyrus, right cuneus. Compared with the Phase II, decreased brain activity in the Phase III was observed in the right precuneus, right posterior cingulate cortex, right angular gyrus. Relative to the Phase I, Significantly increased brain activity in the Phase III was observed in the right calcarine gyrus, right cuneus, and bilateral postcentral gyri. While decreased ReHo values were found in the right posterior cingulate cortex, right angular gyrus, right precuneus; and 3) Correlation analysis showed that the ReHo values of multiple brain regions in Phase I and Phase III were significantly correlated with the VAS and HRSD-17 scores.Conclusion: This study focuses on the instant and sustained effect in postgraduate students with depression. Our study showed that instant effect produced by EA stimulation at GV20 firstly induced changes in somatosensory and visual area, and then, sustained effect (Phase III) have a higher intensity and more extensive than instant effects. Meanwhile, we provide a visualization way to study the instant effects of head acupoints by using a flexible head coil.Keywords: acupuncture, functional magnetic resonance imaging; fMRI, depression, default mode network; DMN, neuroimagingWei XChen HGuo CTan WZhan SDove Medical Pressarticleacupuncturefunctional magnetic resonance imagingdepressiondefault mode networkneuroimagingNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol Volume 17, Pp 873-883 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	acupuncture functional magnetic resonance imaging depression default mode network neuroimaging Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	acupuncture functional magnetic resonance imaging depression default mode network neuroimaging Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Wei X Chen H Guo C Tan W Zhan S The Instant and Sustained Effect of Electroacupuncture in Postgraduate Students with Depression: An fMRI Study
description	Xiang-yu Wei, Hui Chen, Cui Guo, Wen-li Tan, Song-hua Zhan Department of Radiology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, People’s Republic of ChinaCorrespondence: Song-hua Zhan; Hui ChenDepartment of Radiology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, 528 Zhangheng Road, Pudong New Area, Shanghai, 201203, People’s Republic of ChinaEmail zhansonghua@sina.com; chenhui660245@163.comObjection: This study was a primary study to evaluate the instant and sustained effect of electroacupuncture (EA) at GV20 (Baihui) in postgraduate students with mild depression by using a special flexible head coil.Methods: A total of 20 postgraduate students with mild depression underwent EA stimulation at GV20 and 3 phases of resting-state functional magnetic resonance imaging (rs-fMRI) scanning. Phase I: Preparation (before needle insertion); Phase II: during EA; Phase III: 15 minutes after needle removal. The Rs-fMRI data were processed using DPABI and SPSS 25.Results: 1) ReHo values showed significantly differences in the right posterior cingulate cortex, right calcarine gyrus, right angular gyrus, right precuneus, right cuneus, and bilateral postcentral gyri among Phase I, Phase II and Phase III; 2) Relative to the Phase I, increased brain activity in the Phase II was observed in the bilateral postcentral gyri, right calcarine gyrus, right cuneus. Compared with the Phase II, decreased brain activity in the Phase III was observed in the right precuneus, right posterior cingulate cortex, right angular gyrus. Relative to the Phase I, Significantly increased brain activity in the Phase III was observed in the right calcarine gyrus, right cuneus, and bilateral postcentral gyri. While decreased ReHo values were found in the right posterior cingulate cortex, right angular gyrus, right precuneus; and 3) Correlation analysis showed that the ReHo values of multiple brain regions in Phase I and Phase III were significantly correlated with the VAS and HRSD-17 scores.Conclusion: This study focuses on the instant and sustained effect in postgraduate students with depression. Our study showed that instant effect produced by EA stimulation at GV20 firstly induced changes in somatosensory and visual area, and then, sustained effect (Phase III) have a higher intensity and more extensive than instant effects. Meanwhile, we provide a visualization way to study the instant effects of head acupoints by using a flexible head coil.Keywords: acupuncture, functional magnetic resonance imaging; fMRI, depression, default mode network; DMN, neuroimaging
format	article
author	Wei X Chen H Guo C Tan W Zhan S
author_facet	Wei X Chen H Guo C Tan W Zhan S
author_sort	Wei X
title	The Instant and Sustained Effect of Electroacupuncture in Postgraduate Students with Depression: An fMRI Study
title_short	The Instant and Sustained Effect of Electroacupuncture in Postgraduate Students with Depression: An fMRI Study
title_full	The Instant and Sustained Effect of Electroacupuncture in Postgraduate Students with Depression: An fMRI Study
title_fullStr	The Instant and Sustained Effect of Electroacupuncture in Postgraduate Students with Depression: An fMRI Study
title_full_unstemmed	The Instant and Sustained Effect of Electroacupuncture in Postgraduate Students with Depression: An fMRI Study
title_sort	instant and sustained effect of electroacupuncture in postgraduate students with depression: an fmri study
publisher	Dove Medical Press
publishDate	2021
url	https://doaj.org/article/05edc9baca694d7282e82bf761e0bea7
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The Instant and Sustained Effect of Electroacupuncture in Postgraduate Students with Depression: An fMRI Study

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