Live imaging molecular changes in junctional tension upon VE-cadherin in zebrafish

Mechanical forces play a crucial role during morphogenesis, but how these are sensed and transduced in vivo is not fully understood. Here the authors apply a FRET tension sensor to live zebrafish and study changes in VE-cadherin tension at endothelial cell-cell junctions during arterial maturation.

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Autores principales: Anne Karine Lagendijk, Guillermo A. Gomez, Sungmin Baek, Daniel Hesselson, William E. Hughes, Scott Paterson, Daniel E. Conway, Heinz-Georg Belting, Markus Affolter, Kelly A. Smith, Martin A. Schwartz, Alpha S. Yap, Benjamin M. Hogan
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Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/05f4c034d6774bbe95030ef2e8d3c537
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spelling oai:doaj.org-article:05f4c034d6774bbe95030ef2e8d3c5372021-12-02T17:06:20ZLive imaging molecular changes in junctional tension upon VE-cadherin in zebrafish10.1038/s41467-017-01325-62041-1723https://doaj.org/article/05f4c034d6774bbe95030ef2e8d3c5372017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01325-6https://doaj.org/toc/2041-1723Mechanical forces play a crucial role during morphogenesis, but how these are sensed and transduced in vivo is not fully understood. Here the authors apply a FRET tension sensor to live zebrafish and study changes in VE-cadherin tension at endothelial cell-cell junctions during arterial maturation.Anne Karine LagendijkGuillermo A. GomezSungmin BaekDaniel HesselsonWilliam E. HughesScott PatersonDaniel E. ConwayHeinz-Georg BeltingMarkus AffolterKelly A. SmithMartin A. SchwartzAlpha S. YapBenjamin M. HoganNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Anne Karine Lagendijk
Guillermo A. Gomez
Sungmin Baek
Daniel Hesselson
William E. Hughes
Scott Paterson
Daniel E. Conway
Heinz-Georg Belting
Markus Affolter
Kelly A. Smith
Martin A. Schwartz
Alpha S. Yap
Benjamin M. Hogan
Live imaging molecular changes in junctional tension upon VE-cadherin in zebrafish
description Mechanical forces play a crucial role during morphogenesis, but how these are sensed and transduced in vivo is not fully understood. Here the authors apply a FRET tension sensor to live zebrafish and study changes in VE-cadherin tension at endothelial cell-cell junctions during arterial maturation.
format article
author Anne Karine Lagendijk
Guillermo A. Gomez
Sungmin Baek
Daniel Hesselson
William E. Hughes
Scott Paterson
Daniel E. Conway
Heinz-Georg Belting
Markus Affolter
Kelly A. Smith
Martin A. Schwartz
Alpha S. Yap
Benjamin M. Hogan
author_facet Anne Karine Lagendijk
Guillermo A. Gomez
Sungmin Baek
Daniel Hesselson
William E. Hughes
Scott Paterson
Daniel E. Conway
Heinz-Georg Belting
Markus Affolter
Kelly A. Smith
Martin A. Schwartz
Alpha S. Yap
Benjamin M. Hogan
author_sort Anne Karine Lagendijk
title Live imaging molecular changes in junctional tension upon VE-cadherin in zebrafish
title_short Live imaging molecular changes in junctional tension upon VE-cadherin in zebrafish
title_full Live imaging molecular changes in junctional tension upon VE-cadherin in zebrafish
title_fullStr Live imaging molecular changes in junctional tension upon VE-cadherin in zebrafish
title_full_unstemmed Live imaging molecular changes in junctional tension upon VE-cadherin in zebrafish
title_sort live imaging molecular changes in junctional tension upon ve-cadherin in zebrafish
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/05f4c034d6774bbe95030ef2e8d3c537
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AT guillermoagomez liveimagingmolecularchangesinjunctionaltensionuponvecadherininzebrafish
AT sungminbaek liveimagingmolecularchangesinjunctionaltensionuponvecadherininzebrafish
AT danielhesselson liveimagingmolecularchangesinjunctionaltensionuponvecadherininzebrafish
AT williamehughes liveimagingmolecularchangesinjunctionaltensionuponvecadherininzebrafish
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AT alphasyap liveimagingmolecularchangesinjunctionaltensionuponvecadherininzebrafish
AT benjaminmhogan liveimagingmolecularchangesinjunctionaltensionuponvecadherininzebrafish
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