Live imaging molecular changes in junctional tension upon VE-cadherin in zebrafish
Mechanical forces play a crucial role during morphogenesis, but how these are sensed and transduced in vivo is not fully understood. Here the authors apply a FRET tension sensor to live zebrafish and study changes in VE-cadherin tension at endothelial cell-cell junctions during arterial maturation.
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Nature Portfolio
2017
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oai:doaj.org-article:05f4c034d6774bbe95030ef2e8d3c5372021-12-02T17:06:20ZLive imaging molecular changes in junctional tension upon VE-cadherin in zebrafish10.1038/s41467-017-01325-62041-1723https://doaj.org/article/05f4c034d6774bbe95030ef2e8d3c5372017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01325-6https://doaj.org/toc/2041-1723Mechanical forces play a crucial role during morphogenesis, but how these are sensed and transduced in vivo is not fully understood. Here the authors apply a FRET tension sensor to live zebrafish and study changes in VE-cadherin tension at endothelial cell-cell junctions during arterial maturation.Anne Karine LagendijkGuillermo A. GomezSungmin BaekDaniel HesselsonWilliam E. HughesScott PatersonDaniel E. ConwayHeinz-Georg BeltingMarkus AffolterKelly A. SmithMartin A. SchwartzAlpha S. YapBenjamin M. HoganNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017) |
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Science Q |
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Science Q Anne Karine Lagendijk Guillermo A. Gomez Sungmin Baek Daniel Hesselson William E. Hughes Scott Paterson Daniel E. Conway Heinz-Georg Belting Markus Affolter Kelly A. Smith Martin A. Schwartz Alpha S. Yap Benjamin M. Hogan Live imaging molecular changes in junctional tension upon VE-cadherin in zebrafish |
description |
Mechanical forces play a crucial role during morphogenesis, but how these are sensed and transduced in vivo is not fully understood. Here the authors apply a FRET tension sensor to live zebrafish and study changes in VE-cadherin tension at endothelial cell-cell junctions during arterial maturation. |
format |
article |
author |
Anne Karine Lagendijk Guillermo A. Gomez Sungmin Baek Daniel Hesselson William E. Hughes Scott Paterson Daniel E. Conway Heinz-Georg Belting Markus Affolter Kelly A. Smith Martin A. Schwartz Alpha S. Yap Benjamin M. Hogan |
author_facet |
Anne Karine Lagendijk Guillermo A. Gomez Sungmin Baek Daniel Hesselson William E. Hughes Scott Paterson Daniel E. Conway Heinz-Georg Belting Markus Affolter Kelly A. Smith Martin A. Schwartz Alpha S. Yap Benjamin M. Hogan |
author_sort |
Anne Karine Lagendijk |
title |
Live imaging molecular changes in junctional tension upon VE-cadherin in zebrafish |
title_short |
Live imaging molecular changes in junctional tension upon VE-cadherin in zebrafish |
title_full |
Live imaging molecular changes in junctional tension upon VE-cadherin in zebrafish |
title_fullStr |
Live imaging molecular changes in junctional tension upon VE-cadherin in zebrafish |
title_full_unstemmed |
Live imaging molecular changes in junctional tension upon VE-cadherin in zebrafish |
title_sort |
live imaging molecular changes in junctional tension upon ve-cadherin in zebrafish |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/05f4c034d6774bbe95030ef2e8d3c537 |
work_keys_str_mv |
AT annekarinelagendijk liveimagingmolecularchangesinjunctionaltensionuponvecadherininzebrafish AT guillermoagomez liveimagingmolecularchangesinjunctionaltensionuponvecadherininzebrafish AT sungminbaek liveimagingmolecularchangesinjunctionaltensionuponvecadherininzebrafish AT danielhesselson liveimagingmolecularchangesinjunctionaltensionuponvecadherininzebrafish AT williamehughes liveimagingmolecularchangesinjunctionaltensionuponvecadherininzebrafish AT scottpaterson liveimagingmolecularchangesinjunctionaltensionuponvecadherininzebrafish AT danieleconway liveimagingmolecularchangesinjunctionaltensionuponvecadherininzebrafish AT heinzgeorgbelting liveimagingmolecularchangesinjunctionaltensionuponvecadherininzebrafish AT markusaffolter liveimagingmolecularchangesinjunctionaltensionuponvecadherininzebrafish AT kellyasmith liveimagingmolecularchangesinjunctionaltensionuponvecadherininzebrafish AT martinaschwartz liveimagingmolecularchangesinjunctionaltensionuponvecadherininzebrafish AT alphasyap liveimagingmolecularchangesinjunctionaltensionuponvecadherininzebrafish AT benjaminmhogan liveimagingmolecularchangesinjunctionaltensionuponvecadherininzebrafish |
_version_ |
1718381595635744768 |