Silencing of NAMPT leads to up-regulation of insulin receptor substrate 1 gene expression in U87 glioma cells

Objective. The aim of the present study was to investigate the effect of adipokine NAMPT (nicotinamide phosphoribosyltransferase) silencing on the expression of genes encoding IRS1 (insulin receptor substrate 1) and some other proliferation related proteins in U87 glioma cells for evaluation of the...

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Autores principales:	Tsymbal Daria O., Minchenko Dmytro O., Luzina Olena Y., Riabovol Olena O., Danilovskyi Serhiy V., Minchenko Oleksandr H.
Formato:	article
Lenguaje:	EN
Publicado:	Sciendo 2020
Materias:	silencing nampt mrna expression irs1 igfbp3 per2 clu bnip3 tpd52 gadd45a u87 glioma cells Diseases of the endocrine glands. Clinical endocrinology RC648-665
Acceso en línea:	https://doaj.org/article/05fb573f64ce4112aff6f630917f4d37
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id	oai:doaj.org-article:05fb573f64ce4112aff6f630917f4d37
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spelling	oai:doaj.org-article:05fb573f64ce4112aff6f630917f4d372021-12-02T19:07:37ZSilencing of NAMPT leads to up-regulation of insulin receptor substrate 1 gene expression in U87 glioma cells1336-032910.2478/enr-2020-0005https://doaj.org/article/05fb573f64ce4112aff6f630917f4d372020-01-01T00:00:00Zhttps://doi.org/10.2478/enr-2020-0005https://doaj.org/toc/1336-0329Objective. The aim of the present study was to investigate the effect of adipokine NAMPT (nicotinamide phosphoribosyltransferase) silencing on the expression of genes encoding IRS1 (insulin receptor substrate 1) and some other proliferation related proteins in U87 glioma cells for evaluation of the possible significance of this adipokine in intergenic interactions.Tsymbal Daria O.Minchenko Dmytro O.Luzina Olena Y.Riabovol Olena O.Danilovskyi Serhiy V.Minchenko Oleksandr H.Sciendoarticlesilencing namptmrna expressionirs1igfbp3per2clubnip3tpd52gadd45au87 glioma cellsDiseases of the endocrine glands. Clinical endocrinologyRC648-665ENEndocrine Regulations, Vol 54, Iss 1, Pp 31-42 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	silencing nampt mrna expression irs1 igfbp3 per2 clu bnip3 tpd52 gadd45a u87 glioma cells Diseases of the endocrine glands. Clinical endocrinology RC648-665
spellingShingle	silencing nampt mrna expression irs1 igfbp3 per2 clu bnip3 tpd52 gadd45a u87 glioma cells Diseases of the endocrine glands. Clinical endocrinology RC648-665 Tsymbal Daria O. Minchenko Dmytro O. Luzina Olena Y. Riabovol Olena O. Danilovskyi Serhiy V. Minchenko Oleksandr H. Silencing of NAMPT leads to up-regulation of insulin receptor substrate 1 gene expression in U87 glioma cells
description	Objective. The aim of the present study was to investigate the effect of adipokine NAMPT (nicotinamide phosphoribosyltransferase) silencing on the expression of genes encoding IRS1 (insulin receptor substrate 1) and some other proliferation related proteins in U87 glioma cells for evaluation of the possible significance of this adipokine in intergenic interactions.
format	article
author	Tsymbal Daria O. Minchenko Dmytro O. Luzina Olena Y. Riabovol Olena O. Danilovskyi Serhiy V. Minchenko Oleksandr H.
author_facet	Tsymbal Daria O. Minchenko Dmytro O. Luzina Olena Y. Riabovol Olena O. Danilovskyi Serhiy V. Minchenko Oleksandr H.
author_sort	Tsymbal Daria O.
title	Silencing of NAMPT leads to up-regulation of insulin receptor substrate 1 gene expression in U87 glioma cells
title_short	Silencing of NAMPT leads to up-regulation of insulin receptor substrate 1 gene expression in U87 glioma cells
title_full	Silencing of NAMPT leads to up-regulation of insulin receptor substrate 1 gene expression in U87 glioma cells
title_fullStr	Silencing of NAMPT leads to up-regulation of insulin receptor substrate 1 gene expression in U87 glioma cells
title_full_unstemmed	Silencing of NAMPT leads to up-regulation of insulin receptor substrate 1 gene expression in U87 glioma cells
title_sort	silencing of nampt leads to up-regulation of insulin receptor substrate 1 gene expression in u87 glioma cells
publisher	Sciendo
publishDate	2020
url	https://doaj.org/article/05fb573f64ce4112aff6f630917f4d37
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Silencing of NAMPT leads to up-regulation of insulin receptor substrate 1 gene expression in U87 glioma cells

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