Long non-coding RNAs discriminate the stages and gene regulatory states of human humoral immune response

Long non-coding RNAs (lncRNA) constitute a large fraction of human transcriptome, and are reported, individually, for context-specific regulatory functions. Here the authors expand our understanding by providing a systemic, unbiased annotation of lncRNA to establish an atlas of lncRNA landscape duri...

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Autores principales: Xabier Agirre, Cem Meydan, Yanwen Jiang, Leire Garate, Ashley S. Doane, Zhuoning Li, Akanksha Verma, Bruno Paiva, José I. Martín-Subero, Olivier Elemento, Christopher E. Mason, Felipe Prosper, Ari Melnick
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/05fdd715a72c49e894038be6d9a78247
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spelling oai:doaj.org-article:05fdd715a72c49e894038be6d9a782472021-12-02T17:02:17ZLong non-coding RNAs discriminate the stages and gene regulatory states of human humoral immune response10.1038/s41467-019-08679-z2041-1723https://doaj.org/article/05fdd715a72c49e894038be6d9a782472019-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08679-zhttps://doaj.org/toc/2041-1723Long non-coding RNAs (lncRNA) constitute a large fraction of human transcriptome, and are reported, individually, for context-specific regulatory functions. Here the authors expand our understanding by providing a systemic, unbiased annotation of lncRNA to establish an atlas of lncRNA landscape during the induction of human humoral immune responses.Xabier AgirreCem MeydanYanwen JiangLeire GarateAshley S. DoaneZhuoning LiAkanksha VermaBruno PaivaJosé I. Martín-SuberoOlivier ElementoChristopher E. MasonFelipe ProsperAri MelnickNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Xabier Agirre
Cem Meydan
Yanwen Jiang
Leire Garate
Ashley S. Doane
Zhuoning Li
Akanksha Verma
Bruno Paiva
José I. Martín-Subero
Olivier Elemento
Christopher E. Mason
Felipe Prosper
Ari Melnick
Long non-coding RNAs discriminate the stages and gene regulatory states of human humoral immune response
description Long non-coding RNAs (lncRNA) constitute a large fraction of human transcriptome, and are reported, individually, for context-specific regulatory functions. Here the authors expand our understanding by providing a systemic, unbiased annotation of lncRNA to establish an atlas of lncRNA landscape during the induction of human humoral immune responses.
format article
author Xabier Agirre
Cem Meydan
Yanwen Jiang
Leire Garate
Ashley S. Doane
Zhuoning Li
Akanksha Verma
Bruno Paiva
José I. Martín-Subero
Olivier Elemento
Christopher E. Mason
Felipe Prosper
Ari Melnick
author_facet Xabier Agirre
Cem Meydan
Yanwen Jiang
Leire Garate
Ashley S. Doane
Zhuoning Li
Akanksha Verma
Bruno Paiva
José I. Martín-Subero
Olivier Elemento
Christopher E. Mason
Felipe Prosper
Ari Melnick
author_sort Xabier Agirre
title Long non-coding RNAs discriminate the stages and gene regulatory states of human humoral immune response
title_short Long non-coding RNAs discriminate the stages and gene regulatory states of human humoral immune response
title_full Long non-coding RNAs discriminate the stages and gene regulatory states of human humoral immune response
title_fullStr Long non-coding RNAs discriminate the stages and gene regulatory states of human humoral immune response
title_full_unstemmed Long non-coding RNAs discriminate the stages and gene regulatory states of human humoral immune response
title_sort long non-coding rnas discriminate the stages and gene regulatory states of human humoral immune response
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/05fdd715a72c49e894038be6d9a78247
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