Transcriptional programming using engineered systems of transcription factors and genetic architectures
Successful approaches for controlling gene expression modulate mRNA synthesis by coupling it to inducible transcription effectors. Here the authors design 27 non-natural and non-synonymous transcription factors.
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Nature Portfolio
2019
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oai:doaj.org-article:0610868a78794543aba1275ef4df4b1f2021-12-02T15:36:03ZTranscriptional programming using engineered systems of transcription factors and genetic architectures10.1038/s41467-019-12706-42041-1723https://doaj.org/article/0610868a78794543aba1275ef4df4b1f2019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12706-4https://doaj.org/toc/2041-1723Successful approaches for controlling gene expression modulate mRNA synthesis by coupling it to inducible transcription effectors. Here the authors design 27 non-natural and non-synonymous transcription factors.Ronald E. RondonThomas M. GrosecloseAndrew E. ShortCorey J. WilsonNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019) |
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Science Q Ronald E. Rondon Thomas M. Groseclose Andrew E. Short Corey J. Wilson Transcriptional programming using engineered systems of transcription factors and genetic architectures |
description |
Successful approaches for controlling gene expression modulate mRNA synthesis by coupling it to inducible transcription effectors. Here the authors design 27 non-natural and non-synonymous transcription factors. |
format |
article |
author |
Ronald E. Rondon Thomas M. Groseclose Andrew E. Short Corey J. Wilson |
author_facet |
Ronald E. Rondon Thomas M. Groseclose Andrew E. Short Corey J. Wilson |
author_sort |
Ronald E. Rondon |
title |
Transcriptional programming using engineered systems of transcription factors and genetic architectures |
title_short |
Transcriptional programming using engineered systems of transcription factors and genetic architectures |
title_full |
Transcriptional programming using engineered systems of transcription factors and genetic architectures |
title_fullStr |
Transcriptional programming using engineered systems of transcription factors and genetic architectures |
title_full_unstemmed |
Transcriptional programming using engineered systems of transcription factors and genetic architectures |
title_sort |
transcriptional programming using engineered systems of transcription factors and genetic architectures |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/0610868a78794543aba1275ef4df4b1f |
work_keys_str_mv |
AT ronalderondon transcriptionalprogrammingusingengineeredsystemsoftranscriptionfactorsandgeneticarchitectures AT thomasmgroseclose transcriptionalprogrammingusingengineeredsystemsoftranscriptionfactorsandgeneticarchitectures AT andreweshort transcriptionalprogrammingusingengineeredsystemsoftranscriptionfactorsandgeneticarchitectures AT coreyjwilson transcriptionalprogrammingusingengineeredsystemsoftranscriptionfactorsandgeneticarchitectures |
_version_ |
1718386332652273664 |