A comprehensive, mechanistically detailed, and executable model of the cell division cycle in Saccharomyces cerevisiae
Whole-cell models hold great promise for fundamental and translational biology, but genome-scale modelling of signalling networks has been a challenge. Here, the authors present a genome-scale, mechanistic and executable model of the network controlling and executing the S. cerevisiae cell cycle.
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Nature Portfolio
2019
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oai:doaj.org-article:0615cfea666e4b4e822c127ef09470452021-12-02T15:35:12ZA comprehensive, mechanistically detailed, and executable model of the cell division cycle in Saccharomyces cerevisiae10.1038/s41467-019-08903-w2041-1723https://doaj.org/article/0615cfea666e4b4e822c127ef09470452019-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08903-whttps://doaj.org/toc/2041-1723Whole-cell models hold great promise for fundamental and translational biology, but genome-scale modelling of signalling networks has been a challenge. Here, the authors present a genome-scale, mechanistic and executable model of the network controlling and executing the S. cerevisiae cell cycle.Ulrike MünznerEdda KlippMarcus KrantzNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019) |
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Science Q Ulrike Münzner Edda Klipp Marcus Krantz A comprehensive, mechanistically detailed, and executable model of the cell division cycle in Saccharomyces cerevisiae |
description |
Whole-cell models hold great promise for fundamental and translational biology, but genome-scale modelling of signalling networks has been a challenge. Here, the authors present a genome-scale, mechanistic and executable model of the network controlling and executing the S. cerevisiae cell cycle. |
format |
article |
author |
Ulrike Münzner Edda Klipp Marcus Krantz |
author_facet |
Ulrike Münzner Edda Klipp Marcus Krantz |
author_sort |
Ulrike Münzner |
title |
A comprehensive, mechanistically detailed, and executable model of the cell division cycle in Saccharomyces cerevisiae |
title_short |
A comprehensive, mechanistically detailed, and executable model of the cell division cycle in Saccharomyces cerevisiae |
title_full |
A comprehensive, mechanistically detailed, and executable model of the cell division cycle in Saccharomyces cerevisiae |
title_fullStr |
A comprehensive, mechanistically detailed, and executable model of the cell division cycle in Saccharomyces cerevisiae |
title_full_unstemmed |
A comprehensive, mechanistically detailed, and executable model of the cell division cycle in Saccharomyces cerevisiae |
title_sort |
comprehensive, mechanistically detailed, and executable model of the cell division cycle in saccharomyces cerevisiae |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/0615cfea666e4b4e822c127ef0947045 |
work_keys_str_mv |
AT ulrikemunzner acomprehensivemechanisticallydetailedandexecutablemodelofthecelldivisioncycleinsaccharomycescerevisiae AT eddaklipp acomprehensivemechanisticallydetailedandexecutablemodelofthecelldivisioncycleinsaccharomycescerevisiae AT marcuskrantz acomprehensivemechanisticallydetailedandexecutablemodelofthecelldivisioncycleinsaccharomycescerevisiae AT ulrikemunzner comprehensivemechanisticallydetailedandexecutablemodelofthecelldivisioncycleinsaccharomycescerevisiae AT eddaklipp comprehensivemechanisticallydetailedandexecutablemodelofthecelldivisioncycleinsaccharomycescerevisiae AT marcuskrantz comprehensivemechanisticallydetailedandexecutablemodelofthecelldivisioncycleinsaccharomycescerevisiae |
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1718386576460873728 |