Chromatin swelling drives neutrophil extracellular trap release

Neutrophilic granulocytes release their own DNA (NETosis) as neutrophil extracellular traps to capture pathogens. Here, the authors use time-resolved fluorescence and atomic force microscopy and reveal that NETosis is highly organized into three distinct phases with a clear point of no return define...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Elsa Neubert, Daniel Meyer, Francesco Rocca, Gökhan Günay, Anja Kwaczala-Tessmann, Julia Grandke, Susanne Senger-Sander, Claudia Geisler, Alexander Egner, Michael P. Schön, Luise Erpenbeck, Sebastian Kruss
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0628350439624c81af6083195836523c
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:0628350439624c81af6083195836523c
record_format	dspace
spelling	oai:doaj.org-article:0628350439624c81af6083195836523c2021-12-02T14:39:28ZChromatin swelling drives neutrophil extracellular trap release10.1038/s41467-018-06263-52041-1723https://doaj.org/article/0628350439624c81af6083195836523c2018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06263-5https://doaj.org/toc/2041-1723Neutrophilic granulocytes release their own DNA (NETosis) as neutrophil extracellular traps to capture pathogens. Here, the authors use time-resolved fluorescence and atomic force microscopy and reveal that NETosis is highly organized into three distinct phases with a clear point of no return defined by chromatin status.Elsa NeubertDaniel MeyerFrancesco RoccaGökhan GünayAnja Kwaczala-TessmannJulia GrandkeSusanne Senger-SanderClaudia GeislerAlexander EgnerMichael P. SchönLuise ErpenbeckSebastian KrussNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Elsa Neubert Daniel Meyer Francesco Rocca Gökhan Günay Anja Kwaczala-Tessmann Julia Grandke Susanne Senger-Sander Claudia Geisler Alexander Egner Michael P. Schön Luise Erpenbeck Sebastian Kruss Chromatin swelling drives neutrophil extracellular trap release
description	Neutrophilic granulocytes release their own DNA (NETosis) as neutrophil extracellular traps to capture pathogens. Here, the authors use time-resolved fluorescence and atomic force microscopy and reveal that NETosis is highly organized into three distinct phases with a clear point of no return defined by chromatin status.
format	article
author	Elsa Neubert Daniel Meyer Francesco Rocca Gökhan Günay Anja Kwaczala-Tessmann Julia Grandke Susanne Senger-Sander Claudia Geisler Alexander Egner Michael P. Schön Luise Erpenbeck Sebastian Kruss
author_facet	Elsa Neubert Daniel Meyer Francesco Rocca Gökhan Günay Anja Kwaczala-Tessmann Julia Grandke Susanne Senger-Sander Claudia Geisler Alexander Egner Michael P. Schön Luise Erpenbeck Sebastian Kruss
author_sort	Elsa Neubert
title	Chromatin swelling drives neutrophil extracellular trap release
title_short	Chromatin swelling drives neutrophil extracellular trap release
title_full	Chromatin swelling drives neutrophil extracellular trap release
title_fullStr	Chromatin swelling drives neutrophil extracellular trap release
title_full_unstemmed	Chromatin swelling drives neutrophil extracellular trap release
title_sort	chromatin swelling drives neutrophil extracellular trap release
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/0628350439624c81af6083195836523c
work_keys_str_mv	AT elsaneubert chromatinswellingdrivesneutrophilextracellulartraprelease AT danielmeyer chromatinswellingdrivesneutrophilextracellulartraprelease AT francescorocca chromatinswellingdrivesneutrophilextracellulartraprelease AT gokhangunay chromatinswellingdrivesneutrophilextracellulartraprelease AT anjakwaczalatessmann chromatinswellingdrivesneutrophilextracellulartraprelease AT juliagrandke chromatinswellingdrivesneutrophilextracellulartraprelease AT susannesengersander chromatinswellingdrivesneutrophilextracellulartraprelease AT claudiageisler chromatinswellingdrivesneutrophilextracellulartraprelease AT alexanderegner chromatinswellingdrivesneutrophilextracellulartraprelease AT michaelpschon chromatinswellingdrivesneutrophilextracellulartraprelease AT luiseerpenbeck chromatinswellingdrivesneutrophilextracellulartraprelease AT sebastiankruss chromatinswellingdrivesneutrophilextracellulartraprelease
_version_	1718390575099543552

Chromatin swelling drives neutrophil extracellular trap release

Ejemplares similares