Structural basis for specific single-stranded RNA recognition by designer pentatricopeptide repeat proteins

Structural basis for specific single-stranded RNA recognition by designer pentatricopeptide repeat proteins

Pentatricopeptide repeat (PPR) proteins bind RNA and are involved in the regulation of RNA metabolism in eukaryotes. Here, the authors examine the capability of these proteins as modules for gene manipulation using structural biology methods.

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Auteurs principaux: Cuicui Shen, Delin Zhang, Zeyuan Guan, Yexing Liu, Zhao Yang, Yan Yang, Xiang Wang, Qiang Wang, QunXia Zhang, Shilong Fan, Tingting Zou, Ping Yin
Format: article
Langue:EN
Publié: Nature Portfolio 2016
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Science
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Accès en ligne:https://doaj.org/article/064577fdc6c844ef945dfa2fce6de3a9
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Résumé:Pentatricopeptide repeat (PPR) proteins bind RNA and are involved in the regulation of RNA metabolism in eukaryotes. Here, the authors examine the capability of these proteins as modules for gene manipulation using structural biology methods.

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