Heterocyclic sterol probes for live monitoring of sterol trafficking and lysosomal storage disorders

Abstract The monitoring of intracellular cholesterol homeostasis and trafficking is of great importance because their imbalance leads to many pathologies. Reliable tools for cholesterol detection are in demand. This study presents the design and synthesis of fluorescent probes for cholesterol recogn...

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Autores principales: Jarmila Králová, Michal Jurášek, Lucie Krčová, Bohumil Dolenský, Ivan Novotný, Michal Dušek, Zdeňka Rottnerová, Michal Kahle, Pavel Drašar, Petr Bartůněk, Vladimír Král
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/0647f34dfb5f4375bc68e664338d2298
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