Pulmonary actinomycosis: cytomorphological features

Pulmonary actinomycosis is an uncommon infectious disease. Although the gold standard for diagnosis is histological examination with bacterial culture of lung tissue, cytology samples offer a fast and low-cost alternate diagnostic procedure. The cytology literature on this topic is limited to mostl...

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Autores principales:	Rafael Martínez-Girón, Liron Pantanowitz
Formato:	article
Lenguaje:	EN
Publicado:	PAGEPress Publications 2021
Materias:	Pulmonary actinomycosis cytology sputum fine needle aspiration cell blocks Medicine R
Acceso en línea:	https://doaj.org/article/0649a22a13334c139450c0d79ea5e263
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spelling	oai:doaj.org-article:0649a22a13334c139450c0d79ea5e2632021-11-07T07:32:09ZPulmonary actinomycosis: cytomorphological features10.4081/monaldi.2021.16411122-06432532-5264https://doaj.org/article/0649a22a13334c139450c0d79ea5e2632021-11-01T00:00:00Zhttps://www.monaldi-archives.org/index.php/macd/article/view/1641https://doaj.org/toc/1122-0643https://doaj.org/toc/2532-5264 Pulmonary actinomycosis is an uncommon infectious disease. Although the gold standard for diagnosis is histological examination with bacterial culture of lung tissue, cytology samples offer a fast and low-cost alternate diagnostic procedure. The cytology literature on this topic is limited to mostly case reports. Therefore, the aim of this study was to review cytological material in a series of patients with a diagnosis of pulmonary actinomycosis to characterize the main cytomorphological findings. Different cytological respiratory samples including sputum smears, bronchoalveolar lavages (BALs), transthoracic or endobronchial fine needle aspiration cytology (FNAC) and cell block preparations were used for retrospective examination. For all cases patient age, gender, symptoms, and radiological chest findings were recorded. A total of 26 cytological respiratory samples (14 sputum smears, 9 FNAC, two BALs) including direct smears and 6 cell blocks from 9 patients were examined. In sputum smears the most remarkable findings were the presence of dark cotton ball masses with projections like spider legs and/or mouse tails (75% of the samples). Sulfur granules were observed in 4 (40%) of the sputum smears and within FNAC cases. Various respiratory cytology samples including sputum smears, FNAC and BALs can reveal cytomorphological findings diagnostic of pulmonary actinomycosis. Characteristic cytological findings compatible with a diagnosis of this infection include cotton ball masses and less frequently sulfur granules. Rafael Martínez-GirónLiron PantanowitzPAGEPress PublicationsarticlePulmonary actinomycosiscytologysputumfine needle aspirationcell blocksMedicineRENMonaldi Archives for Chest Disease (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Pulmonary actinomycosis cytology sputum fine needle aspiration cell blocks Medicine R
spellingShingle	Pulmonary actinomycosis cytology sputum fine needle aspiration cell blocks Medicine R Rafael Martínez-Girón Liron Pantanowitz Pulmonary actinomycosis: cytomorphological features
description	Pulmonary actinomycosis is an uncommon infectious disease. Although the gold standard for diagnosis is histological examination with bacterial culture of lung tissue, cytology samples offer a fast and low-cost alternate diagnostic procedure. The cytology literature on this topic is limited to mostly case reports. Therefore, the aim of this study was to review cytological material in a series of patients with a diagnosis of pulmonary actinomycosis to characterize the main cytomorphological findings. Different cytological respiratory samples including sputum smears, bronchoalveolar lavages (BALs), transthoracic or endobronchial fine needle aspiration cytology (FNAC) and cell block preparations were used for retrospective examination. For all cases patient age, gender, symptoms, and radiological chest findings were recorded. A total of 26 cytological respiratory samples (14 sputum smears, 9 FNAC, two BALs) including direct smears and 6 cell blocks from 9 patients were examined. In sputum smears the most remarkable findings were the presence of dark cotton ball masses with projections like spider legs and/or mouse tails (75% of the samples). Sulfur granules were observed in 4 (40%) of the sputum smears and within FNAC cases. Various respiratory cytology samples including sputum smears, FNAC and BALs can reveal cytomorphological findings diagnostic of pulmonary actinomycosis. Characteristic cytological findings compatible with a diagnosis of this infection include cotton ball masses and less frequently sulfur granules.
format	article
author	Rafael Martínez-Girón Liron Pantanowitz
author_facet	Rafael Martínez-Girón Liron Pantanowitz
author_sort	Rafael Martínez-Girón
title	Pulmonary actinomycosis: cytomorphological features
title_short	Pulmonary actinomycosis: cytomorphological features
title_full	Pulmonary actinomycosis: cytomorphological features
title_fullStr	Pulmonary actinomycosis: cytomorphological features
title_full_unstemmed	Pulmonary actinomycosis: cytomorphological features
title_sort	pulmonary actinomycosis: cytomorphological features
publisher	PAGEPress Publications
publishDate	2021
url	https://doaj.org/article/0649a22a13334c139450c0d79ea5e263
work_keys_str_mv	AT rafaelmartinezgiron pulmonaryactinomycosiscytomorphologicalfeatures AT lironpantanowitz pulmonaryactinomycosiscytomorphologicalfeatures
_version_	1718443527135821824

Pulmonary actinomycosis: cytomorphological features

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