Computer aided designing of novel pyrrolopyridine derivatives as JAK1 inhibitors
Abstract Janus kinases (JAKs) are a family of non-receptor kinases that play a key role in cytokine signaling and their aberrant activities are associated with the pathogenesis of various immune diseases. The JAK1 isoform plays an essential role in the types 1 and II interferon signaling and elicits...
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Autores principales: | Seketoulie Keretsu, Suparna Ghosh, Seung Joo Cho |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/064aa1af3b8144639f85b32b9b179cb3 |
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