Gallic acid oxidation products alter the formation pathway of insulin amyloid fibrils

Abstract Amyloidogenic protein assembly into insoluble fibrillar aggregates is linked with several neurodegenerative disorders, such as Alzheimer’s or Parkinson’s disease, affecting millions of people worldwide. The search for a potential anti-amyloid drug has led to the discovery of hundreds of com...

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Autores principales: Andrius Sakalauskas, Mantas Ziaunys, Vytautas Smirnovas
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/0651154ecfd040219a51e76802256ef8
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