Hierarchical modeling for rare event detection and cell subset alignment across flow cytometry samples.

Flow cytometry is the prototypical assay for multi-parameter single cell analysis, and is essential in vaccine and biomarker research for the enumeration of antigen-specific lymphocytes that are often found in extremely low frequencies (0.1% or less). Standard analysis of flow cytometry data relies...

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Autores principales: Andrew Cron, Cécile Gouttefangeas, Jacob Frelinger, Lin Lin, Satwinder K Singh, Cedrik M Britten, Marij J P Welters, Sjoerd H van der Burg, Mike West, Cliburn Chan
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/06513624c96542608300c537b0a8b6af
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