Long noncoding RNA NRON contributes to HIV-1 latency by specifically inducing tat protein degradation

Long noncoding RNAs have a wide range of physiological functions, though their role in viral infection and latency is poorly understood. Here the authors show a lncRNA NRON can induce degradation of HIV-1 protein Tat, potentially contributing to latent infection.

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Autores principales:	Jun Li, Cancan Chen, Xiancai Ma, Guannan Geng, Bingfeng Liu, Yijun Zhang, Shaoyang Zhang, Fudi Zhong, Chao Liu, Yue Yin, Weiping Cai, Hui Zhang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0658e7370fef4de8af787a5e70268d4a
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spelling	oai:doaj.org-article:0658e7370fef4de8af787a5e70268d4a2021-12-02T16:49:59ZLong noncoding RNA NRON contributes to HIV-1 latency by specifically inducing tat protein degradation10.1038/ncomms117302041-1723https://doaj.org/article/0658e7370fef4de8af787a5e70268d4a2016-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms11730https://doaj.org/toc/2041-1723Long noncoding RNAs have a wide range of physiological functions, though their role in viral infection and latency is poorly understood. Here the authors show a lncRNA NRON can induce degradation of HIV-1 protein Tat, potentially contributing to latent infection.Jun LiCancan ChenXiancai MaGuannan GengBingfeng LiuYijun ZhangShaoyang ZhangFudi ZhongChao LiuYue YinWeiping CaiHui ZhangNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jun Li Cancan Chen Xiancai Ma Guannan Geng Bingfeng Liu Yijun Zhang Shaoyang Zhang Fudi Zhong Chao Liu Yue Yin Weiping Cai Hui Zhang Long noncoding RNA NRON contributes to HIV-1 latency by specifically inducing tat protein degradation
description	Long noncoding RNAs have a wide range of physiological functions, though their role in viral infection and latency is poorly understood. Here the authors show a lncRNA NRON can induce degradation of HIV-1 protein Tat, potentially contributing to latent infection.
format	article
author	Jun Li Cancan Chen Xiancai Ma Guannan Geng Bingfeng Liu Yijun Zhang Shaoyang Zhang Fudi Zhong Chao Liu Yue Yin Weiping Cai Hui Zhang
author_facet	Jun Li Cancan Chen Xiancai Ma Guannan Geng Bingfeng Liu Yijun Zhang Shaoyang Zhang Fudi Zhong Chao Liu Yue Yin Weiping Cai Hui Zhang
author_sort	Jun Li
title	Long noncoding RNA NRON contributes to HIV-1 latency by specifically inducing tat protein degradation
title_short	Long noncoding RNA NRON contributes to HIV-1 latency by specifically inducing tat protein degradation
title_full	Long noncoding RNA NRON contributes to HIV-1 latency by specifically inducing tat protein degradation
title_fullStr	Long noncoding RNA NRON contributes to HIV-1 latency by specifically inducing tat protein degradation
title_full_unstemmed	Long noncoding RNA NRON contributes to HIV-1 latency by specifically inducing tat protein degradation
title_sort	long noncoding rna nron contributes to hiv-1 latency by specifically inducing tat protein degradation
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/0658e7370fef4de8af787a5e70268d4a
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Long noncoding RNA NRON contributes to HIV-1 latency by specifically inducing tat protein degradation

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