A Quantitative Proteomics Approach to Gain Insight into NRF2-KEAP1 Skeletal Muscle System and Its Cysteine Redox Regulation

Mammalian skeletal muscle (SkM) tissue engages the Nrf2-Keap1-dependent antioxidant defense mechanism to respond adaptively to stress. Redox homeostasis mediated by the reversible modification of selective cysteines is the prevalent mode of regulation. The protein targets of SkM redox regulation are...

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Autores principales: Rafay Abu, Li Yu, Ashok Kumar, Lie Gao, Vikas Kumar
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
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IPA
Acceso en línea:https://doaj.org/article/06728d06c1824df38dc15c82956252ca
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