Associations of ultrasound estimated early mid pregnancy visceral and subcutaneous fat depths and early pregnancy BMI with adverse neonatal outcomes

Abstract This study investigated whether maternal central adiposity and body mass index (BMI) were associated with neonatal hypoglycemia and adverse neonatal outcomes. A cohort study was performed at Uppsala University Hospital, Sweden, between 2015 and 2018. Visceral and subcutaneous fat depths wer...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Emelie Lindberger, Anna-Karin Wikström, Eva Bergman, Karin Eurenius, Ajlana Mulic-Lutvica, Linda Lindström, Inger Sundström Poromaa, Fredrik Ahlsson
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/0674eaa65fc245379607332e5073a0a4
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:0674eaa65fc245379607332e5073a0a4
record_format	dspace
spelling	oai:doaj.org-article:0674eaa65fc245379607332e5073a0a42021-12-02T13:20:23ZAssociations of ultrasound estimated early mid pregnancy visceral and subcutaneous fat depths and early pregnancy BMI with adverse neonatal outcomes10.1038/s41598-021-84045-82045-2322https://doaj.org/article/0674eaa65fc245379607332e5073a0a42021-02-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-84045-8https://doaj.org/toc/2045-2322Abstract This study investigated whether maternal central adiposity and body mass index (BMI) were associated with neonatal hypoglycemia and adverse neonatal outcomes. A cohort study was performed at Uppsala University Hospital, Sweden, between 2015 and 2018. Visceral and subcutaneous fat depths were measured by ultrasound at the early second-trimester anomaly scan in 2771 women giving birth to singleton infants. Body mass index was assessed in early pregnancy. Logistic regression models were performed. Adjustments were made for age, BMI (not in model with BMI as exposure), smoking, maternal country of birth, and parity. Outcomes were neonatal hypoglycemia (blood glucose concentration < 2.6 mmol/l), a composite of adverse neonatal outcomes (Apgar < 7 at 5 min of age, or umbilical artery pH ≤ 7.0, or admission to neonatal intensive care unit), and the components of the composite outcome. Visceral and subcutaneous fat depths measured by ultrasound in early mid pregnancy were not associated with any of the outcomes in adjusted analyses. For every unit increase in BMI, the likelihood of neonatal hypoglycemia increased by 5% (aOR 1.05, 95% CI 1.01–1.10), the composite outcome by 5% (aOR 1.05, 95% CI 1.01–1.08), and admission to neonatal intensive care unit by 6% (aOR 1.06, 95% CI 1.02–1.10).Emelie LindbergerAnna-Karin WikströmEva BergmanKarin EureniusAjlana Mulic-LutvicaLinda LindströmInger Sundström PoromaaFredrik AhlssonNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Emelie Lindberger Anna-Karin Wikström Eva Bergman Karin Eurenius Ajlana Mulic-Lutvica Linda Lindström Inger Sundström Poromaa Fredrik Ahlsson Associations of ultrasound estimated early mid pregnancy visceral and subcutaneous fat depths and early pregnancy BMI with adverse neonatal outcomes
description	Abstract This study investigated whether maternal central adiposity and body mass index (BMI) were associated with neonatal hypoglycemia and adverse neonatal outcomes. A cohort study was performed at Uppsala University Hospital, Sweden, between 2015 and 2018. Visceral and subcutaneous fat depths were measured by ultrasound at the early second-trimester anomaly scan in 2771 women giving birth to singleton infants. Body mass index was assessed in early pregnancy. Logistic regression models were performed. Adjustments were made for age, BMI (not in model with BMI as exposure), smoking, maternal country of birth, and parity. Outcomes were neonatal hypoglycemia (blood glucose concentration < 2.6 mmol/l), a composite of adverse neonatal outcomes (Apgar < 7 at 5 min of age, or umbilical artery pH ≤ 7.0, or admission to neonatal intensive care unit), and the components of the composite outcome. Visceral and subcutaneous fat depths measured by ultrasound in early mid pregnancy were not associated with any of the outcomes in adjusted analyses. For every unit increase in BMI, the likelihood of neonatal hypoglycemia increased by 5% (aOR 1.05, 95% CI 1.01–1.10), the composite outcome by 5% (aOR 1.05, 95% CI 1.01–1.08), and admission to neonatal intensive care unit by 6% (aOR 1.06, 95% CI 1.02–1.10).
format	article
author	Emelie Lindberger Anna-Karin Wikström Eva Bergman Karin Eurenius Ajlana Mulic-Lutvica Linda Lindström Inger Sundström Poromaa Fredrik Ahlsson
author_facet	Emelie Lindberger Anna-Karin Wikström Eva Bergman Karin Eurenius Ajlana Mulic-Lutvica Linda Lindström Inger Sundström Poromaa Fredrik Ahlsson
author_sort	Emelie Lindberger
title	Associations of ultrasound estimated early mid pregnancy visceral and subcutaneous fat depths and early pregnancy BMI with adverse neonatal outcomes
title_short	Associations of ultrasound estimated early mid pregnancy visceral and subcutaneous fat depths and early pregnancy BMI with adverse neonatal outcomes
title_full	Associations of ultrasound estimated early mid pregnancy visceral and subcutaneous fat depths and early pregnancy BMI with adverse neonatal outcomes
title_fullStr	Associations of ultrasound estimated early mid pregnancy visceral and subcutaneous fat depths and early pregnancy BMI with adverse neonatal outcomes
title_full_unstemmed	Associations of ultrasound estimated early mid pregnancy visceral and subcutaneous fat depths and early pregnancy BMI with adverse neonatal outcomes
title_sort	associations of ultrasound estimated early mid pregnancy visceral and subcutaneous fat depths and early pregnancy bmi with adverse neonatal outcomes
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/0674eaa65fc245379607332e5073a0a4
work_keys_str_mv	AT emelielindberger associationsofultrasoundestimatedearlymidpregnancyvisceralandsubcutaneousfatdepthsandearlypregnancybmiwithadverseneonataloutcomes AT annakarinwikstrom associationsofultrasoundestimatedearlymidpregnancyvisceralandsubcutaneousfatdepthsandearlypregnancybmiwithadverseneonataloutcomes AT evabergman associationsofultrasoundestimatedearlymidpregnancyvisceralandsubcutaneousfatdepthsandearlypregnancybmiwithadverseneonataloutcomes AT karineurenius associationsofultrasoundestimatedearlymidpregnancyvisceralandsubcutaneousfatdepthsandearlypregnancybmiwithadverseneonataloutcomes AT ajlanamuliclutvica associationsofultrasoundestimatedearlymidpregnancyvisceralandsubcutaneousfatdepthsandearlypregnancybmiwithadverseneonataloutcomes AT lindalindstrom associationsofultrasoundestimatedearlymidpregnancyvisceralandsubcutaneousfatdepthsandearlypregnancybmiwithadverseneonataloutcomes AT ingersundstromporomaa associationsofultrasoundestimatedearlymidpregnancyvisceralandsubcutaneousfatdepthsandearlypregnancybmiwithadverseneonataloutcomes AT fredrikahlsson associationsofultrasoundestimatedearlymidpregnancyvisceralandsubcutaneousfatdepthsandearlypregnancybmiwithadverseneonataloutcomes
_version_	1718393191546224640

Associations of ultrasound estimated early mid pregnancy visceral and subcutaneous fat depths and early pregnancy BMI with adverse neonatal outcomes

Ejemplares similares