Epidemiological and phylogenetic analysis reveals Flavobacteriaceae as potential ancestral source of tigecycline resistance gene tet(X)

Epidemiological and phylogenetic analysis reveals Flavobacteriaceae as potential ancestral source of tigecycline resistance gene tet(X)

Emergence of tigecycline-resistance tet(X) genes is of concern. Here, the authors determine tet(X) prevalence in more than 6,000 clinical Gram-negative bacterial isolates collected between 1994 to 2019 in hospitals in China and suggest that Flavobacteriaceae could be the potential ancestral source o...

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Autores principales: Rong Zhang, Ning Dong, Zhangqi Shen, Yu Zeng, Jiauyue Lu, Congcong Liu, Hongwei Zhou, Yanyan Hu, Qiaoling Sun, Qipeng Cheng, Lingbing Shu, Jiachang Cai, Edward Wai-Chi Chan, Gongxiang Chen, Sheng Chen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/0677705344a246088c24e061207395a7
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spelling oai:doaj.org-article:0677705344a246088c24e061207395a72021-12-02T18:34:03ZEpidemiological and phylogenetic analysis reveals Flavobacteriaceae as potential ancestral source of tigecycline resistance gene tet(X)10.1038/s41467-020-18475-92041-1723https://doaj.org/article/0677705344a246088c24e061207395a72020-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18475-9https://doaj.org/toc/2041-1723Emergence of tigecycline-resistance tet(X) genes is of concern. Here, the authors determine tet(X) prevalence in more than 6,000 clinical Gram-negative bacterial isolates collected between 1994 to 2019 in hospitals in China and suggest that Flavobacteriaceae could be the potential ancestral source of the tigecycline resistance genes.Rong ZhangNing DongZhangqi ShenYu ZengJiauyue LuCongcong LiuHongwei ZhouYanyan HuQiaoling SunQipeng ChengLingbing ShuJiachang CaiEdward Wai-Chi ChanGongxiang ChenSheng ChenNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Rong Zhang
Ning Dong
Zhangqi Shen
Yu Zeng
Jiauyue Lu
Congcong Liu
Hongwei Zhou
Yanyan Hu
Qiaoling Sun
Qipeng Cheng
Lingbing Shu
Jiachang Cai
Edward Wai-Chi Chan
Gongxiang Chen
Sheng Chen
Epidemiological and phylogenetic analysis reveals Flavobacteriaceae as potential ancestral source of tigecycline resistance gene tet(X)
description Emergence of tigecycline-resistance tet(X) genes is of concern. Here, the authors determine tet(X) prevalence in more than 6,000 clinical Gram-negative bacterial isolates collected between 1994 to 2019 in hospitals in China and suggest that Flavobacteriaceae could be the potential ancestral source of the tigecycline resistance genes.
format article
author Rong Zhang
Ning Dong
Zhangqi Shen
Yu Zeng
Jiauyue Lu
Congcong Liu
Hongwei Zhou
Yanyan Hu
Qiaoling Sun
Qipeng Cheng
Lingbing Shu
Jiachang Cai
Edward Wai-Chi Chan
Gongxiang Chen
Sheng Chen
author_facet Rong Zhang
Ning Dong
Zhangqi Shen
Yu Zeng
Jiauyue Lu
Congcong Liu
Hongwei Zhou
Yanyan Hu
Qiaoling Sun
Qipeng Cheng
Lingbing Shu
Jiachang Cai
Edward Wai-Chi Chan
Gongxiang Chen
Sheng Chen
author_sort Rong Zhang
title Epidemiological and phylogenetic analysis reveals Flavobacteriaceae as potential ancestral source of tigecycline resistance gene tet(X)
title_short Epidemiological and phylogenetic analysis reveals Flavobacteriaceae as potential ancestral source of tigecycline resistance gene tet(X)
title_full Epidemiological and phylogenetic analysis reveals Flavobacteriaceae as potential ancestral source of tigecycline resistance gene tet(X)
title_fullStr Epidemiological and phylogenetic analysis reveals Flavobacteriaceae as potential ancestral source of tigecycline resistance gene tet(X)
title_full_unstemmed Epidemiological and phylogenetic analysis reveals Flavobacteriaceae as potential ancestral source of tigecycline resistance gene tet(X)
title_sort epidemiological and phylogenetic analysis reveals flavobacteriaceae as potential ancestral source of tigecycline resistance gene tet(x)
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/0677705344a246088c24e061207395a7
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