Expert recommendations on blood purification treatment protocol for patients with severe COVID-19

Coronavirus disease (COVID-19) was first diagnosed in Wuhan in December 2019. The World Health Organization defined the subsequent outbreak of COVID-19 worldwide as a public health emergency of international concern. Epidemiological data indicate that at least 20% of COVID-19 patients have severe di...

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Autores principales:	Xiang-Hong Yang, Ren-Hua Sun, Ming-Yan Zhao, Er-Zhen Chen, Jiao Liu, Hong-Liang Wang, Rong-Li Yang, De-Chang Chen
Formato:	article
Lenguaje:	EN
Publicado:	KeAi Communications Co., Ltd. 2020
Materias:	COVID-19 Blood purification treatment SARS-CoV-2 Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/06810ccab53d49149b1c0067fe2b3803
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spelling	oai:doaj.org-article:06810ccab53d49149b1c0067fe2b38032021-12-02T15:56:13ZExpert recommendations on blood purification treatment protocol for patients with severe COVID-192095-882X10.1016/j.cdtm.2020.04.002https://doaj.org/article/06810ccab53d49149b1c0067fe2b38032020-06-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2095882X20300372https://doaj.org/toc/2095-882XCoronavirus disease (COVID-19) was first diagnosed in Wuhan in December 2019. The World Health Organization defined the subsequent outbreak of COVID-19 worldwide as a public health emergency of international concern. Epidemiological data indicate that at least 20% of COVID-19 patients have severe disease. In addition to impairment of the respiratory system, acute kidney injury (AKI) is a major complication. Immune damage mediated by cytokine storms and concomitant AKI is a key factor for poor prognosis. Based on previous experience of blood purification for patients with severe acute respiratory syndrome and Middle East respiratory syndrome combined with clinical front-line practice, we developed a blood purification protocol for patients with severe COVID-19. This protocol is divided into four major steps. The first step is to assess whether patients with severe COVID-19 require blood purification. The second step is to prescribe a blood purification treatment for patients with COVID-19. The third step is to monitor and adjust parameters of blood purification. The fourth step is to evaluate the timing of discontinuation of blood purification. It is expected that blood purification will play a key role in effectively reducing the mortality of patients with severe COVID-19 through the standardized implementation of the present protocol.Xiang-Hong YangRen-Hua SunMing-Yan ZhaoEr-Zhen ChenJiao LiuHong-Liang WangRong-Li YangDe-Chang ChenKeAi Communications Co., Ltd.articleCOVID-19Blood purification treatmentSARS-CoV-2Medicine (General)R5-920ENChronic Diseases and Translational Medicine, Vol 6, Iss 2, Pp 106-114 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	COVID-19 Blood purification treatment SARS-CoV-2 Medicine (General) R5-920
spellingShingle	COVID-19 Blood purification treatment SARS-CoV-2 Medicine (General) R5-920 Xiang-Hong Yang Ren-Hua Sun Ming-Yan Zhao Er-Zhen Chen Jiao Liu Hong-Liang Wang Rong-Li Yang De-Chang Chen Expert recommendations on blood purification treatment protocol for patients with severe COVID-19
description	Coronavirus disease (COVID-19) was first diagnosed in Wuhan in December 2019. The World Health Organization defined the subsequent outbreak of COVID-19 worldwide as a public health emergency of international concern. Epidemiological data indicate that at least 20% of COVID-19 patients have severe disease. In addition to impairment of the respiratory system, acute kidney injury (AKI) is a major complication. Immune damage mediated by cytokine storms and concomitant AKI is a key factor for poor prognosis. Based on previous experience of blood purification for patients with severe acute respiratory syndrome and Middle East respiratory syndrome combined with clinical front-line practice, we developed a blood purification protocol for patients with severe COVID-19. This protocol is divided into four major steps. The first step is to assess whether patients with severe COVID-19 require blood purification. The second step is to prescribe a blood purification treatment for patients with COVID-19. The third step is to monitor and adjust parameters of blood purification. The fourth step is to evaluate the timing of discontinuation of blood purification. It is expected that blood purification will play a key role in effectively reducing the mortality of patients with severe COVID-19 through the standardized implementation of the present protocol.
format	article
author	Xiang-Hong Yang Ren-Hua Sun Ming-Yan Zhao Er-Zhen Chen Jiao Liu Hong-Liang Wang Rong-Li Yang De-Chang Chen
author_facet	Xiang-Hong Yang Ren-Hua Sun Ming-Yan Zhao Er-Zhen Chen Jiao Liu Hong-Liang Wang Rong-Li Yang De-Chang Chen
author_sort	Xiang-Hong Yang
title	Expert recommendations on blood purification treatment protocol for patients with severe COVID-19
title_short	Expert recommendations on blood purification treatment protocol for patients with severe COVID-19
title_full	Expert recommendations on blood purification treatment protocol for patients with severe COVID-19
title_fullStr	Expert recommendations on blood purification treatment protocol for patients with severe COVID-19
title_full_unstemmed	Expert recommendations on blood purification treatment protocol for patients with severe COVID-19
title_sort	expert recommendations on blood purification treatment protocol for patients with severe covid-19
publisher	KeAi Communications Co., Ltd.
publishDate	2020
url	https://doaj.org/article/06810ccab53d49149b1c0067fe2b3803
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Expert recommendations on blood purification treatment protocol for patients with severe COVID-19

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