FREQUENCY OF BETA THALASSEMIA TRAIT AMONG THE HEALTHY INDIVIDUALS - A SINGLE CENTRE STUDY

Objective: To determine the frequency of beta thalassemia trait among the asymptomatic healthy individuals. Study Design: Cross sectional study. Place and Duration of Study: This was carried out at Pakistan Air Force (PAF) Hospital Lahore from Jan 2016 to Jun 2017. Patients and Methods:...

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Autores principales:	Muhammad Arif Sadiq, Ahmad Muqeem, Rizwan Yusuf, Asma Bilal
Formato:	article
Lenguaje:	EN
Publicado:	Army Medical College Rawalpindi 2018
Materias:	thalassemia haemoglobinopathies Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/068ceeed4b52414d8ec86861f33c3ef8
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spelling	oai:doaj.org-article:068ceeed4b52414d8ec86861f33c3ef82021-11-30T02:46:43ZFREQUENCY OF BETA THALASSEMIA TRAIT AMONG THE HEALTHY INDIVIDUALS - A SINGLE CENTRE STUDY0030-96482411-8842https://doaj.org/article/068ceeed4b52414d8ec86861f33c3ef82018-12-01T00:00:00Zhttps://www.pafmj.org/index.php/PAFMJ/article/view/2594/2116https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To determine the frequency of beta thalassemia trait among the asymptomatic healthy individuals. Study Design: Cross sectional study. Place and Duration of Study: This was carried out at Pakistan Air Force (PAF) Hospital Lahore from Jan 2016 to Jun 2017. Patients and Methods: The subjects were both male and female who came from all over Pakistan for central medical board for selection in Pakistan Air Force. Their ages were between 18 and 28 years. Their complete blood counts were measured on Sysmex KX 21 hematology analyzer. Candidates with microcytic hypochromic indices without anaemia were screened for beta thalassemia trait. Haemoglobin (Hb) electrophoresis was done on cellulose acetate paper at alkaline PH. HbA2 estimation was done by measuring the absorbance of elute on spectrophotometer. Beta thalassemia was diagnosed if the subject had HbA2 more than 3.5%. The data was analyzed using statistical package for social sciences (SPSS) software version 17. Results: A total of 2279 individual were enrolled in the study. Among them 2061 (90.4%) were males and 218 (9.6%) were females. Out of 2061 males, 91 (4.41%) were found to have beta thalassemia trait whereas among females only 6 (2.75%) out of 218 had beta thalassemia trait. The overall frequency of beta thalassemia trait was found to be 4.25%. Conclusion: The overall frequency of beta thalassemia trait in our study was found to be 4.25%. Thalassemia screening should be carried out along with normal health screening tests at least once in lifetime.Muhammad Arif SadiqAhmad MuqeemRizwan YusufAsma BilalArmy Medical College RawalpindiarticlethalassemiahaemoglobinopathiesMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 68, Iss 6, Pp 1716-1719 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	thalassemia haemoglobinopathies Medicine R Medicine (General) R5-920
spellingShingle	thalassemia haemoglobinopathies Medicine R Medicine (General) R5-920 Muhammad Arif Sadiq Ahmad Muqeem Rizwan Yusuf Asma Bilal FREQUENCY OF BETA THALASSEMIA TRAIT AMONG THE HEALTHY INDIVIDUALS - A SINGLE CENTRE STUDY
description	Objective: To determine the frequency of beta thalassemia trait among the asymptomatic healthy individuals. Study Design: Cross sectional study. Place and Duration of Study: This was carried out at Pakistan Air Force (PAF) Hospital Lahore from Jan 2016 to Jun 2017. Patients and Methods: The subjects were both male and female who came from all over Pakistan for central medical board for selection in Pakistan Air Force. Their ages were between 18 and 28 years. Their complete blood counts were measured on Sysmex KX 21 hematology analyzer. Candidates with microcytic hypochromic indices without anaemia were screened for beta thalassemia trait. Haemoglobin (Hb) electrophoresis was done on cellulose acetate paper at alkaline PH. HbA2 estimation was done by measuring the absorbance of elute on spectrophotometer. Beta thalassemia was diagnosed if the subject had HbA2 more than 3.5%. The data was analyzed using statistical package for social sciences (SPSS) software version 17. Results: A total of 2279 individual were enrolled in the study. Among them 2061 (90.4%) were males and 218 (9.6%) were females. Out of 2061 males, 91 (4.41%) were found to have beta thalassemia trait whereas among females only 6 (2.75%) out of 218 had beta thalassemia trait. The overall frequency of beta thalassemia trait was found to be 4.25%. Conclusion: The overall frequency of beta thalassemia trait in our study was found to be 4.25%. Thalassemia screening should be carried out along with normal health screening tests at least once in lifetime.
format	article
author	Muhammad Arif Sadiq Ahmad Muqeem Rizwan Yusuf Asma Bilal
author_facet	Muhammad Arif Sadiq Ahmad Muqeem Rizwan Yusuf Asma Bilal
author_sort	Muhammad Arif Sadiq
title	FREQUENCY OF BETA THALASSEMIA TRAIT AMONG THE HEALTHY INDIVIDUALS - A SINGLE CENTRE STUDY
title_short	FREQUENCY OF BETA THALASSEMIA TRAIT AMONG THE HEALTHY INDIVIDUALS - A SINGLE CENTRE STUDY
title_full	FREQUENCY OF BETA THALASSEMIA TRAIT AMONG THE HEALTHY INDIVIDUALS - A SINGLE CENTRE STUDY
title_fullStr	FREQUENCY OF BETA THALASSEMIA TRAIT AMONG THE HEALTHY INDIVIDUALS - A SINGLE CENTRE STUDY
title_full_unstemmed	FREQUENCY OF BETA THALASSEMIA TRAIT AMONG THE HEALTHY INDIVIDUALS - A SINGLE CENTRE STUDY
title_sort	frequency of beta thalassemia trait among the healthy individuals - a single centre study
publisher	Army Medical College Rawalpindi
publishDate	2018
url	https://doaj.org/article/068ceeed4b52414d8ec86861f33c3ef8
work_keys_str_mv	AT muhammadarifsadiq frequencyofbetathalassemiatraitamongthehealthyindividualsasinglecentrestudy AT ahmadmuqeem frequencyofbetathalassemiatraitamongthehealthyindividualsasinglecentrestudy AT rizwanyusuf frequencyofbetathalassemiatraitamongthehealthyindividualsasinglecentrestudy AT asmabilal frequencyofbetathalassemiatraitamongthehealthyindividualsasinglecentrestudy
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FREQUENCY OF BETA THALASSEMIA TRAIT AMONG THE HEALTHY INDIVIDUALS - A SINGLE CENTRE STUDY

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