Temporal and compartment-specific signals coordinate mitotic exit with spindle position

The mitotic exit network (MEN) triggers mitotic exit and can be blocked by the spindle position checkpoint (SPOC). Here the authors show that SPOC kinase Kin4 counterbalances MEN activation by the Cdc fourteen early anaphase release (FEAR) network in the mother cell and that in the absence of FEAR m...

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Autores principales:	Ayse Koca Caydasi, Anton Khmelinskii, Rafael Duenas-Sanchez, Bahtiyar Kurtulmus, Michael Knop, Gislene Pereira
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/069c4b5c13744c27951446be503830d8
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spelling	oai:doaj.org-article:069c4b5c13744c27951446be503830d82021-12-02T17:06:09ZTemporal and compartment-specific signals coordinate mitotic exit with spindle position10.1038/ncomms141292041-1723https://doaj.org/article/069c4b5c13744c27951446be503830d82017-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms14129https://doaj.org/toc/2041-1723The mitotic exit network (MEN) triggers mitotic exit and can be blocked by the spindle position checkpoint (SPOC). Here the authors show that SPOC kinase Kin4 counterbalances MEN activation by the Cdc fourteen early anaphase release (FEAR) network in the mother cell and that in the absence of FEAR mitotic exit requires daughter cell-confined factors.Ayse Koca CaydasiAnton KhmelinskiiRafael Duenas-SanchezBahtiyar KurtulmusMichael KnopGislene PereiraNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ayse Koca Caydasi Anton Khmelinskii Rafael Duenas-Sanchez Bahtiyar Kurtulmus Michael Knop Gislene Pereira Temporal and compartment-specific signals coordinate mitotic exit with spindle position
description	The mitotic exit network (MEN) triggers mitotic exit and can be blocked by the spindle position checkpoint (SPOC). Here the authors show that SPOC kinase Kin4 counterbalances MEN activation by the Cdc fourteen early anaphase release (FEAR) network in the mother cell and that in the absence of FEAR mitotic exit requires daughter cell-confined factors.
format	article
author	Ayse Koca Caydasi Anton Khmelinskii Rafael Duenas-Sanchez Bahtiyar Kurtulmus Michael Knop Gislene Pereira
author_facet	Ayse Koca Caydasi Anton Khmelinskii Rafael Duenas-Sanchez Bahtiyar Kurtulmus Michael Knop Gislene Pereira
author_sort	Ayse Koca Caydasi
title	Temporal and compartment-specific signals coordinate mitotic exit with spindle position
title_short	Temporal and compartment-specific signals coordinate mitotic exit with spindle position
title_full	Temporal and compartment-specific signals coordinate mitotic exit with spindle position
title_fullStr	Temporal and compartment-specific signals coordinate mitotic exit with spindle position
title_full_unstemmed	Temporal and compartment-specific signals coordinate mitotic exit with spindle position
title_sort	temporal and compartment-specific signals coordinate mitotic exit with spindle position
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/069c4b5c13744c27951446be503830d8
work_keys_str_mv	AT aysekocacaydasi temporalandcompartmentspecificsignalscoordinatemitoticexitwithspindleposition AT antonkhmelinskii temporalandcompartmentspecificsignalscoordinatemitoticexitwithspindleposition AT rafaelduenassanchez temporalandcompartmentspecificsignalscoordinatemitoticexitwithspindleposition AT bahtiyarkurtulmus temporalandcompartmentspecificsignalscoordinatemitoticexitwithspindleposition AT michaelknop temporalandcompartmentspecificsignalscoordinatemitoticexitwithspindleposition AT gislenepereira temporalandcompartmentspecificsignalscoordinatemitoticexitwithspindleposition
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Temporal and compartment-specific signals coordinate mitotic exit with spindle position

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