Sex differences in fear memory consolidation via Tac2 signaling in mice

The Tachykinin 2 (Tac2) pathway in the central amygdala is sufficient and necessary for modulating fear memory consolidation. The authors show that silencing Tac2 neurons in the amygdala of male mice reduces fear expression, while fear expression in female mice is increased when manipulations are ma...

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Autores principales: A. Florido, E. R. Velasco, C. M. Soto-Faguás, A. Gomez-Gomez, L. Perez-Caballero, P. Molina, R. Nadal, O. J. Pozo, C. A. Saura, R. Andero
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/069d3bc10a55439ba681f05b81c4f6bc
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Sumario:The Tachykinin 2 (Tac2) pathway in the central amygdala is sufficient and necessary for modulating fear memory consolidation. The authors show that silencing Tac2 neurons in the amygdala of male mice reduces fear expression, while fear expression in female mice is increased when manipulations are made during proestrus.