Age-dependent appearance of SARS-CoV-2 entry sites in mouse chemosensory systems reflects COVID-19 anosmia-ageusia symptoms

Brechbühl et al characterise the gene and protein expression of ACE2/TMPRSS2 in the mouse olfactory and gustatory cells, which reveals that SARS-CoV-2 target cells are of basal and sensory origin. They also demonstrate an age-dependent appearance of viral entry-sites, which could inform the use of m...

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Autores principales: Julien Brechbühl, Ana Catarina Lopes, Dean Wood, Sofiane Bouteiller, Aurélie de Vallière, Chantal Verdumo, Marie-Christine Broillet
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/06aa80b59488459288a1f04810b31b74
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