Association of variations in HLA class II and other loci with susceptibility to EGFR-mutated lung adenocarcinoma
EGFR mutations in lung adenocarcinoma are more frequent in East Asians compared to other populations. Here, the authors carry out a genome-wide association study in EGFRmutant cancers and identify loci that are associated with risk of developing this molecular subtype of cancer.
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Nature Portfolio
2016
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oai:doaj.org-article:06abe374e88a4c0f861cb8193ced8a5f2021-12-02T17:32:08ZAssociation of variations in HLA class II and other loci with susceptibility to EGFR-mutated lung adenocarcinoma10.1038/ncomms124512041-1723https://doaj.org/article/06abe374e88a4c0f861cb8193ced8a5f2016-08-01T00:00:00Zhttps://doi.org/10.1038/ncomms12451https://doaj.org/toc/2041-1723EGFR mutations in lung adenocarcinoma are more frequent in East Asians compared to other populations. Here, the authors carry out a genome-wide association study in EGFRmutant cancers and identify loci that are associated with risk of developing this molecular subtype of cancer.Kouya ShiraishiYukinori OkadaAtsushi TakahashiYoichiro KamataniYukihide MomozawaKyota AshikawaHideo KunitohShingo MatsumotoAtsushi TakanoKimihiro ShimizuAkiteru GotoKoji TsutaShun-ichi WatanabeYuichiro OheYukio WatanabeYasushi GotoHiroshi NokiharaKoh FurutaAkihiko YoshidaKoichi GotoTomoyuki HishidaMasahiro TsuboiKatsuya TsuchiharaYohei MiyagiHaruhiko NakayamaTomoyuki YokoseKazumi TanakaToshiteru NagashimaYoichi OhtakiDaichi MaedaKazuhiro ImaiYoshihiro MinamiyaHiromi SakamotoAkira SaitoYoko ShimadaKuniko SunamiMotonobu SaitoJohji InazawaYusuke NakamuraTeruhiko YoshidaJun YokotaFumihiko MatsudaKeitaro MatsuoYataro DaigoMichiaki KuboTakashi KohnoNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-7 (2016) |
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Science Q Kouya Shiraishi Yukinori Okada Atsushi Takahashi Yoichiro Kamatani Yukihide Momozawa Kyota Ashikawa Hideo Kunitoh Shingo Matsumoto Atsushi Takano Kimihiro Shimizu Akiteru Goto Koji Tsuta Shun-ichi Watanabe Yuichiro Ohe Yukio Watanabe Yasushi Goto Hiroshi Nokihara Koh Furuta Akihiko Yoshida Koichi Goto Tomoyuki Hishida Masahiro Tsuboi Katsuya Tsuchihara Yohei Miyagi Haruhiko Nakayama Tomoyuki Yokose Kazumi Tanaka Toshiteru Nagashima Yoichi Ohtaki Daichi Maeda Kazuhiro Imai Yoshihiro Minamiya Hiromi Sakamoto Akira Saito Yoko Shimada Kuniko Sunami Motonobu Saito Johji Inazawa Yusuke Nakamura Teruhiko Yoshida Jun Yokota Fumihiko Matsuda Keitaro Matsuo Yataro Daigo Michiaki Kubo Takashi Kohno Association of variations in HLA class II and other loci with susceptibility to EGFR-mutated lung adenocarcinoma |
| description |
EGFR mutations in lung adenocarcinoma are more frequent in East Asians compared to other populations. Here, the authors carry out a genome-wide association study in EGFRmutant cancers and identify loci that are associated with risk of developing this molecular subtype of cancer. |
| format |
article |
| author |
Kouya Shiraishi Yukinori Okada Atsushi Takahashi Yoichiro Kamatani Yukihide Momozawa Kyota Ashikawa Hideo Kunitoh Shingo Matsumoto Atsushi Takano Kimihiro Shimizu Akiteru Goto Koji Tsuta Shun-ichi Watanabe Yuichiro Ohe Yukio Watanabe Yasushi Goto Hiroshi Nokihara Koh Furuta Akihiko Yoshida Koichi Goto Tomoyuki Hishida Masahiro Tsuboi Katsuya Tsuchihara Yohei Miyagi Haruhiko Nakayama Tomoyuki Yokose Kazumi Tanaka Toshiteru Nagashima Yoichi Ohtaki Daichi Maeda Kazuhiro Imai Yoshihiro Minamiya Hiromi Sakamoto Akira Saito Yoko Shimada Kuniko Sunami Motonobu Saito Johji Inazawa Yusuke Nakamura Teruhiko Yoshida Jun Yokota Fumihiko Matsuda Keitaro Matsuo Yataro Daigo Michiaki Kubo Takashi Kohno |
| author_facet |
Kouya Shiraishi Yukinori Okada Atsushi Takahashi Yoichiro Kamatani Yukihide Momozawa Kyota Ashikawa Hideo Kunitoh Shingo Matsumoto Atsushi Takano Kimihiro Shimizu Akiteru Goto Koji Tsuta Shun-ichi Watanabe Yuichiro Ohe Yukio Watanabe Yasushi Goto Hiroshi Nokihara Koh Furuta Akihiko Yoshida Koichi Goto Tomoyuki Hishida Masahiro Tsuboi Katsuya Tsuchihara Yohei Miyagi Haruhiko Nakayama Tomoyuki Yokose Kazumi Tanaka Toshiteru Nagashima Yoichi Ohtaki Daichi Maeda Kazuhiro Imai Yoshihiro Minamiya Hiromi Sakamoto Akira Saito Yoko Shimada Kuniko Sunami Motonobu Saito Johji Inazawa Yusuke Nakamura Teruhiko Yoshida Jun Yokota Fumihiko Matsuda Keitaro Matsuo Yataro Daigo Michiaki Kubo Takashi Kohno |
| author_sort |
Kouya Shiraishi |
| title |
Association of variations in HLA class II and other loci with susceptibility to EGFR-mutated lung adenocarcinoma |
| title_short |
Association of variations in HLA class II and other loci with susceptibility to EGFR-mutated lung adenocarcinoma |
| title_full |
Association of variations in HLA class II and other loci with susceptibility to EGFR-mutated lung adenocarcinoma |
| title_fullStr |
Association of variations in HLA class II and other loci with susceptibility to EGFR-mutated lung adenocarcinoma |
| title_full_unstemmed |
Association of variations in HLA class II and other loci with susceptibility to EGFR-mutated lung adenocarcinoma |
| title_sort |
association of variations in hla class ii and other loci with susceptibility to egfr-mutated lung adenocarcinoma |
| publisher |
Nature Portfolio |
| publishDate |
2016 |
| url |
https://doaj.org/article/06abe374e88a4c0f861cb8193ced8a5f |
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