Markers of Polyfunctional SARS-CoV-2 Antibodies in Convalescent Plasma

Convalescent plasma has been deployed globally as a treatment for COVID-19, but efficacy has been mixed. Better understanding of the antibody characteristics that may contribute to its antiviral effects is important for this intervention as well as offer insights into correlates of vaccine-mediated...

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Autores principales: Harini Natarajan, Andrew R. Crowley, Savannah E. Butler, Shiwei Xu, Joshua A. Weiner, Evan M. Bloch, Kirsten Littlefield, Wendy Wieland-Alter, Ruth I. Connor, Peter F. Wright, Sarah E. Benner, Tania S. Bonny, Oliver Laeyendecker, David Sullivan, Shmuel Shoham, Thomas C. Quinn, H. Benjamin Larman, Arturo Casadevall, Andrew Pekosz, Andrew D. Redd, Aaron A. R. Tobian, Margaret E. Ackerman
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Publicado: American Society for Microbiology 2021
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Acceso en línea:https://doaj.org/article/06bc9967a2e644a7be0d758babdbd5ad
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spelling oai:doaj.org-article:06bc9967a2e644a7be0d758babdbd5ad2021-11-03T18:56:09ZMarkers of Polyfunctional SARS-CoV-2 Antibodies in Convalescent Plasma2150-751110.1128/mBio.00765-21https://doaj.org/article/06bc9967a2e644a7be0d758babdbd5ad2021-04-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.00765-21https://doaj.org/toc/2150-7511 Convalescent plasma has been deployed globally as a treatment for COVID-19, but efficacy has been mixed. Better understanding of the antibody characteristics that may contribute to its antiviral effects is important for this intervention as well as offer insights into correlates of vaccine-mediated protection.Harini NatarajanAndrew R. CrowleySavannah E. ButlerShiwei XuJoshua A. WeinerEvan M. BlochKirsten LittlefieldWendy Wieland-AlterRuth I. ConnorPeter F. WrightSarah E. BennerTania S. BonnyOliver LaeyendeckerDavid SullivanShmuel ShohamThomas C. QuinnH. Benjamin LarmanArturo CasadevallAndrew PekoszAndrew D. ReddAaron A. R. TobianMargaret E. AckermanAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 2 (2021)
institution DOAJ
collection DOAJ
language EN
topic Microbiology
QR1-502
spellingShingle Microbiology
QR1-502
Harini Natarajan
Andrew R. Crowley
Savannah E. Butler
Shiwei Xu
Joshua A. Weiner
Evan M. Bloch
Kirsten Littlefield
Wendy Wieland-Alter
Ruth I. Connor
Peter F. Wright
Sarah E. Benner
Tania S. Bonny
Oliver Laeyendecker
David Sullivan
Shmuel Shoham
Thomas C. Quinn
H. Benjamin Larman
Arturo Casadevall
Andrew Pekosz
Andrew D. Redd
Aaron A. R. Tobian
Margaret E. Ackerman
Markers of Polyfunctional SARS-CoV-2 Antibodies in Convalescent Plasma
description Convalescent plasma has been deployed globally as a treatment for COVID-19, but efficacy has been mixed. Better understanding of the antibody characteristics that may contribute to its antiviral effects is important for this intervention as well as offer insights into correlates of vaccine-mediated protection.
format article
author Harini Natarajan
Andrew R. Crowley
Savannah E. Butler
Shiwei Xu
Joshua A. Weiner
Evan M. Bloch
Kirsten Littlefield
Wendy Wieland-Alter
Ruth I. Connor
Peter F. Wright
Sarah E. Benner
Tania S. Bonny
Oliver Laeyendecker
David Sullivan
Shmuel Shoham
Thomas C. Quinn
H. Benjamin Larman
Arturo Casadevall
Andrew Pekosz
Andrew D. Redd
Aaron A. R. Tobian
Margaret E. Ackerman
author_facet Harini Natarajan
Andrew R. Crowley
Savannah E. Butler
Shiwei Xu
Joshua A. Weiner
Evan M. Bloch
Kirsten Littlefield
Wendy Wieland-Alter
Ruth I. Connor
Peter F. Wright
Sarah E. Benner
Tania S. Bonny
Oliver Laeyendecker
David Sullivan
Shmuel Shoham
Thomas C. Quinn
H. Benjamin Larman
Arturo Casadevall
Andrew Pekosz
Andrew D. Redd
Aaron A. R. Tobian
Margaret E. Ackerman
author_sort Harini Natarajan
title Markers of Polyfunctional SARS-CoV-2 Antibodies in Convalescent Plasma
title_short Markers of Polyfunctional SARS-CoV-2 Antibodies in Convalescent Plasma
title_full Markers of Polyfunctional SARS-CoV-2 Antibodies in Convalescent Plasma
title_fullStr Markers of Polyfunctional SARS-CoV-2 Antibodies in Convalescent Plasma
title_full_unstemmed Markers of Polyfunctional SARS-CoV-2 Antibodies in Convalescent Plasma
title_sort markers of polyfunctional sars-cov-2 antibodies in convalescent plasma
publisher American Society for Microbiology
publishDate 2021
url https://doaj.org/article/06bc9967a2e644a7be0d758babdbd5ad
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