Hsp90 Inhibition: A Promising Therapeutic Approach for ARSACS

Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is a neurodegenerative disease caused by mutations in the <i>SACS</i> gene, encoding the 520 kDa modular protein sacsin, which comprises multiple functional sequence domains that suggest a role either as a scaffold in pro...

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Autores principales: Suran Nethisinghe, Rosella Abeti, Maheswaran Kesavan, W. Christian Wigley, Paola Giunti
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/06be726115614437a0d4ce65adfa79f7
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