Cryo-EM structure of catalytic ribonucleoprotein complex RNase MRP
Ribozyme-based RNase MRP is an essential eukaryotic enzyme involved in the maturation of rRNA and is evolutionarily related to RNase P. Here, the authors present the 3.0 Å cryo-EM structure of the S. cerevisiae RNase MRP holoenzyme, a 450 kDa ribonucleoprotein complex and compare it with RNase P....
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Nature Portfolio
2020
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oai:doaj.org-article:06c391967b3f4eb3af021d620c244d8d2021-12-02T18:34:08ZCryo-EM structure of catalytic ribonucleoprotein complex RNase MRP10.1038/s41467-020-17308-z2041-1723https://doaj.org/article/06c391967b3f4eb3af021d620c244d8d2020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17308-zhttps://doaj.org/toc/2041-1723Ribozyme-based RNase MRP is an essential eukaryotic enzyme involved in the maturation of rRNA and is evolutionarily related to RNase P. Here, the authors present the 3.0 Å cryo-EM structure of the S. cerevisiae RNase MRP holoenzyme, a 450 kDa ribonucleoprotein complex and compare it with RNase P.Anna PerederinaDi LiHyunwook LeeCarol BatorIgor BerezinSusan L. HafensteinAndrey S. KrasilnikovNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020) |
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Science Q Anna Perederina Di Li Hyunwook Lee Carol Bator Igor Berezin Susan L. Hafenstein Andrey S. Krasilnikov Cryo-EM structure of catalytic ribonucleoprotein complex RNase MRP |
description |
Ribozyme-based RNase MRP is an essential eukaryotic enzyme involved in the maturation of rRNA and is evolutionarily related to RNase P. Here, the authors present the 3.0 Å cryo-EM structure of the S. cerevisiae RNase MRP holoenzyme, a 450 kDa ribonucleoprotein complex and compare it with RNase P. |
format |
article |
author |
Anna Perederina Di Li Hyunwook Lee Carol Bator Igor Berezin Susan L. Hafenstein Andrey S. Krasilnikov |
author_facet |
Anna Perederina Di Li Hyunwook Lee Carol Bator Igor Berezin Susan L. Hafenstein Andrey S. Krasilnikov |
author_sort |
Anna Perederina |
title |
Cryo-EM structure of catalytic ribonucleoprotein complex RNase MRP |
title_short |
Cryo-EM structure of catalytic ribonucleoprotein complex RNase MRP |
title_full |
Cryo-EM structure of catalytic ribonucleoprotein complex RNase MRP |
title_fullStr |
Cryo-EM structure of catalytic ribonucleoprotein complex RNase MRP |
title_full_unstemmed |
Cryo-EM structure of catalytic ribonucleoprotein complex RNase MRP |
title_sort |
cryo-em structure of catalytic ribonucleoprotein complex rnase mrp |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/06c391967b3f4eb3af021d620c244d8d |
work_keys_str_mv |
AT annaperederina cryoemstructureofcatalyticribonucleoproteincomplexrnasemrp AT dili cryoemstructureofcatalyticribonucleoproteincomplexrnasemrp AT hyunwooklee cryoemstructureofcatalyticribonucleoproteincomplexrnasemrp AT carolbator cryoemstructureofcatalyticribonucleoproteincomplexrnasemrp AT igorberezin cryoemstructureofcatalyticribonucleoproteincomplexrnasemrp AT susanlhafenstein cryoemstructureofcatalyticribonucleoproteincomplexrnasemrp AT andreyskrasilnikov cryoemstructureofcatalyticribonucleoproteincomplexrnasemrp |
_version_ |
1718377901156466688 |