Lamin B1 is required for mature neuron-specific gene expression during olfactory sensory neuron differentiation

Emerging evidence suggests that lamins regulate gene expression during cellular differentiation. Giganteet al. show that lamin B1 is necessary for the upregulation of mature neuron-specific genes during olfactory neuron differentiation, and its deficiency leads to attenuated olfactory neuron respons...

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Autores principales: Crystal M. Gigante, Michele Dibattista, Frederick N. Dong, Xiaobin Zheng, Sibiao Yue, Stephen G. Young, Johannes Reisert, Yixian Zheng, Haiqing Zhao
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/06c5b6b1249f4e8c888b50d8e1c2fe8e
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spelling oai:doaj.org-article:06c5b6b1249f4e8c888b50d8e1c2fe8e2021-12-02T17:06:04ZLamin B1 is required for mature neuron-specific gene expression during olfactory sensory neuron differentiation10.1038/ncomms150982041-1723https://doaj.org/article/06c5b6b1249f4e8c888b50d8e1c2fe8e2017-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms15098https://doaj.org/toc/2041-1723Emerging evidence suggests that lamins regulate gene expression during cellular differentiation. Giganteet al. show that lamin B1 is necessary for the upregulation of mature neuron-specific genes during olfactory neuron differentiation, and its deficiency leads to attenuated olfactory neuron response to odour in mice.Crystal M. GiganteMichele DibattistaFrederick N. DongXiaobin ZhengSibiao YueStephen G. YoungJohannes ReisertYixian ZhengHaiqing ZhaoNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Crystal M. Gigante
Michele Dibattista
Frederick N. Dong
Xiaobin Zheng
Sibiao Yue
Stephen G. Young
Johannes Reisert
Yixian Zheng
Haiqing Zhao
Lamin B1 is required for mature neuron-specific gene expression during olfactory sensory neuron differentiation
description Emerging evidence suggests that lamins regulate gene expression during cellular differentiation. Giganteet al. show that lamin B1 is necessary for the upregulation of mature neuron-specific genes during olfactory neuron differentiation, and its deficiency leads to attenuated olfactory neuron response to odour in mice.
format article
author Crystal M. Gigante
Michele Dibattista
Frederick N. Dong
Xiaobin Zheng
Sibiao Yue
Stephen G. Young
Johannes Reisert
Yixian Zheng
Haiqing Zhao
author_facet Crystal M. Gigante
Michele Dibattista
Frederick N. Dong
Xiaobin Zheng
Sibiao Yue
Stephen G. Young
Johannes Reisert
Yixian Zheng
Haiqing Zhao
author_sort Crystal M. Gigante
title Lamin B1 is required for mature neuron-specific gene expression during olfactory sensory neuron differentiation
title_short Lamin B1 is required for mature neuron-specific gene expression during olfactory sensory neuron differentiation
title_full Lamin B1 is required for mature neuron-specific gene expression during olfactory sensory neuron differentiation
title_fullStr Lamin B1 is required for mature neuron-specific gene expression during olfactory sensory neuron differentiation
title_full_unstemmed Lamin B1 is required for mature neuron-specific gene expression during olfactory sensory neuron differentiation
title_sort lamin b1 is required for mature neuron-specific gene expression during olfactory sensory neuron differentiation
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/06c5b6b1249f4e8c888b50d8e1c2fe8e
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