Anthropogenic interferences lead to gut microbiome dysbiosis in Asian elephants and may alter adaptation processes to surrounding environments

Abstract Human activities interfere with wild animals and lead to the loss of many animal populations. Therefore, efforts have been made to understand how wildlife can rebound from anthropogenic disturbances. An essential mechanism to adapt to environmental and social changes is the fluctuations in...

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Autores principales:	Mohamed Abdallah Mohamed Moustafa, Hla Myet Chel, May June Thu, Saw Bawm, Lat Lat Htun, Mar Mar Win, Zaw Min Oo, Natsuo Ohsawa, Mirkka Lahdenperä, Wessam Mohamed Ahmed Mohamed, Kimihito Ito, Nariaki Nonaka, Ryo Nakao, Ken Katakura
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/06cb1c73668745ebb73b53957ac008c4
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spelling	oai:doaj.org-article:06cb1c73668745ebb73b53957ac008c42021-12-02T14:01:21ZAnthropogenic interferences lead to gut microbiome dysbiosis in Asian elephants and may alter adaptation processes to surrounding environments10.1038/s41598-020-80537-12045-2322https://doaj.org/article/06cb1c73668745ebb73b53957ac008c42021-01-01T00:00:00Zhttps://doi.org/10.1038/s41598-020-80537-1https://doaj.org/toc/2045-2322Abstract Human activities interfere with wild animals and lead to the loss of many animal populations. Therefore, efforts have been made to understand how wildlife can rebound from anthropogenic disturbances. An essential mechanism to adapt to environmental and social changes is the fluctuations in the host gut microbiome. Here we give a comprehensive description of anthropogenically induced microbiome alterations in Asian elephants (n = 30). We detected gut microbial changes due to overseas translocation, captivity and deworming. We found that microbes belonging to Planococcaceae had the highest contribution in the microbiome alterations after translocation, while Clostridiaceae, Spirochaetaceae and Bacteroidia were the most affected after captivity. However, deworming significantly changed the abundance of Flavobacteriaceae, Sphingobacteriaceae, Xanthomonadaceae, Weeksellaceae and Burkholderiaceae. These findings may provide fundamental ideas to help guide the preservation tactics and probiotic replacement therapies of a dysbiosed gut microbiome in Asian elephants. More generally, these results show the severity of anthropogenic activities at the level of gut microbiome, altering the adaptation processes to new environments and the subsequent capability to maintain normal physiological processes in animals.Mohamed Abdallah Mohamed MoustafaHla Myet ChelMay June ThuSaw BawmLat Lat HtunMar Mar WinZaw Min OoNatsuo OhsawaMirkka LahdenperäWessam Mohamed Ahmed MohamedKimihito ItoNariaki NonakaRyo NakaoKen KatakuraNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Mohamed Abdallah Mohamed Moustafa Hla Myet Chel May June Thu Saw Bawm Lat Lat Htun Mar Mar Win Zaw Min Oo Natsuo Ohsawa Mirkka Lahdenperä Wessam Mohamed Ahmed Mohamed Kimihito Ito Nariaki Nonaka Ryo Nakao Ken Katakura Anthropogenic interferences lead to gut microbiome dysbiosis in Asian elephants and may alter adaptation processes to surrounding environments
description	Abstract Human activities interfere with wild animals and lead to the loss of many animal populations. Therefore, efforts have been made to understand how wildlife can rebound from anthropogenic disturbances. An essential mechanism to adapt to environmental and social changes is the fluctuations in the host gut microbiome. Here we give a comprehensive description of anthropogenically induced microbiome alterations in Asian elephants (n = 30). We detected gut microbial changes due to overseas translocation, captivity and deworming. We found that microbes belonging to Planococcaceae had the highest contribution in the microbiome alterations after translocation, while Clostridiaceae, Spirochaetaceae and Bacteroidia were the most affected after captivity. However, deworming significantly changed the abundance of Flavobacteriaceae, Sphingobacteriaceae, Xanthomonadaceae, Weeksellaceae and Burkholderiaceae. These findings may provide fundamental ideas to help guide the preservation tactics and probiotic replacement therapies of a dysbiosed gut microbiome in Asian elephants. More generally, these results show the severity of anthropogenic activities at the level of gut microbiome, altering the adaptation processes to new environments and the subsequent capability to maintain normal physiological processes in animals.
format	article
author	Mohamed Abdallah Mohamed Moustafa Hla Myet Chel May June Thu Saw Bawm Lat Lat Htun Mar Mar Win Zaw Min Oo Natsuo Ohsawa Mirkka Lahdenperä Wessam Mohamed Ahmed Mohamed Kimihito Ito Nariaki Nonaka Ryo Nakao Ken Katakura
author_facet	Mohamed Abdallah Mohamed Moustafa Hla Myet Chel May June Thu Saw Bawm Lat Lat Htun Mar Mar Win Zaw Min Oo Natsuo Ohsawa Mirkka Lahdenperä Wessam Mohamed Ahmed Mohamed Kimihito Ito Nariaki Nonaka Ryo Nakao Ken Katakura
author_sort	Mohamed Abdallah Mohamed Moustafa
title	Anthropogenic interferences lead to gut microbiome dysbiosis in Asian elephants and may alter adaptation processes to surrounding environments
title_short	Anthropogenic interferences lead to gut microbiome dysbiosis in Asian elephants and may alter adaptation processes to surrounding environments
title_full	Anthropogenic interferences lead to gut microbiome dysbiosis in Asian elephants and may alter adaptation processes to surrounding environments
title_fullStr	Anthropogenic interferences lead to gut microbiome dysbiosis in Asian elephants and may alter adaptation processes to surrounding environments
title_full_unstemmed	Anthropogenic interferences lead to gut microbiome dysbiosis in Asian elephants and may alter adaptation processes to surrounding environments
title_sort	anthropogenic interferences lead to gut microbiome dysbiosis in asian elephants and may alter adaptation processes to surrounding environments
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/06cb1c73668745ebb73b53957ac008c4
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Anthropogenic interferences lead to gut microbiome dysbiosis in Asian elephants and may alter adaptation processes to surrounding environments

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