IFN-gamma-inducible Irga6 mediates host resistance against Chlamydia trachomatis via autophagy.

Chlamydial infection of the host cell induces Gamma interferon (IFNgamma), a central immunoprotector for humans and mice. The primary defense against Chlamydia infection in the mouse involves the IFNgamma-inducible family of IRG proteins; however, the precise mechanisms mediating the pathogen's...

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Autores principales: Munir A Al-Zeer, Hesham M Al-Younes, Peter R Braun, Jens Zerrahn, Thomas F Meyer
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2009
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Acceso en línea:https://doaj.org/article/06ce659de8d347c7b22946df56d30575
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