AUTOANTIBODIES TO GLUTAMIC ACID DECARBOXYLASE AS A PATHOGENETIC MARKER OF TYPE I DIABETES MELLITUS

Abstract. A new method of enzyme-linked immunosorbent assay (in solid-phase ELISA format) has been developed to determine concentrations of autoantibodies to glutamic acid decarboxylase, as well as an evidencebased methodology is proposed for its medical implications, as a quantitative pathogenetic...

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Autores principales: N. V. Piven, L. N. Lukhverchyk, A. I. Burakovsky, N. V. Polegenkaya, M. V. Karpovich
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Lenguaje:RU
Publicado: SPb RAACI 2014
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Acceso en línea:https://doaj.org/article/06cf4f3946f64cc3b21d9c52a17c2f71
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spelling oai:doaj.org-article:06cf4f3946f64cc3b21d9c52a17c2f712021-11-18T08:03:41ZAUTOANTIBODIES TO GLUTAMIC ACID DECARBOXYLASE AS A PATHOGENETIC MARKER OF TYPE I DIABETES MELLITUS1563-06252313-741X10.15789/1563-0625-2011-2-3-257-260https://doaj.org/article/06cf4f3946f64cc3b21d9c52a17c2f712014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/511https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. A new method of enzyme-linked immunosorbent assay (in solid-phase ELISA format) has been developed to determine concentrations of autoantibodies to glutamic acid decarboxylase, as well as an evidencebased methodology is proposed for its medical implications, as a quantitative pathogenetic predictive marker of autoimmune diagnostics in type 1 diabetes mellitus. This technique could be implied for serial production of diagnostic reagent kits, aimed for detection of autoantibodies to glutamic acid decarboxylase by means of ELISA approach. (Med. Immunol., 2011, vol. 13, N 2-3, pp 257-260)N. V. PivenL. N. LukhverchykA. I. BurakovskyN. V. PolegenkayaM. V. KarpovichSPb RAACIarticleautoantibodiesglutamic acid decarboxylaseimmunoenzyme assaydiabetes mellituspathogenesisImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 13, Iss 2-3, Pp 257-260 (2014)
institution DOAJ
collection DOAJ
language RU
topic autoantibodies
glutamic acid decarboxylase
immunoenzyme assay
diabetes mellitus
pathogenesis
Immunologic diseases. Allergy
RC581-607
spellingShingle autoantibodies
glutamic acid decarboxylase
immunoenzyme assay
diabetes mellitus
pathogenesis
Immunologic diseases. Allergy
RC581-607
N. V. Piven
L. N. Lukhverchyk
A. I. Burakovsky
N. V. Polegenkaya
M. V. Karpovich
AUTOANTIBODIES TO GLUTAMIC ACID DECARBOXYLASE AS A PATHOGENETIC MARKER OF TYPE I DIABETES MELLITUS
description Abstract. A new method of enzyme-linked immunosorbent assay (in solid-phase ELISA format) has been developed to determine concentrations of autoantibodies to glutamic acid decarboxylase, as well as an evidencebased methodology is proposed for its medical implications, as a quantitative pathogenetic predictive marker of autoimmune diagnostics in type 1 diabetes mellitus. This technique could be implied for serial production of diagnostic reagent kits, aimed for detection of autoantibodies to glutamic acid decarboxylase by means of ELISA approach. (Med. Immunol., 2011, vol. 13, N 2-3, pp 257-260)
format article
author N. V. Piven
L. N. Lukhverchyk
A. I. Burakovsky
N. V. Polegenkaya
M. V. Karpovich
author_facet N. V. Piven
L. N. Lukhverchyk
A. I. Burakovsky
N. V. Polegenkaya
M. V. Karpovich
author_sort N. V. Piven
title AUTOANTIBODIES TO GLUTAMIC ACID DECARBOXYLASE AS A PATHOGENETIC MARKER OF TYPE I DIABETES MELLITUS
title_short AUTOANTIBODIES TO GLUTAMIC ACID DECARBOXYLASE AS A PATHOGENETIC MARKER OF TYPE I DIABETES MELLITUS
title_full AUTOANTIBODIES TO GLUTAMIC ACID DECARBOXYLASE AS A PATHOGENETIC MARKER OF TYPE I DIABETES MELLITUS
title_fullStr AUTOANTIBODIES TO GLUTAMIC ACID DECARBOXYLASE AS A PATHOGENETIC MARKER OF TYPE I DIABETES MELLITUS
title_full_unstemmed AUTOANTIBODIES TO GLUTAMIC ACID DECARBOXYLASE AS A PATHOGENETIC MARKER OF TYPE I DIABETES MELLITUS
title_sort autoantibodies to glutamic acid decarboxylase as a pathogenetic marker of type i diabetes mellitus
publisher SPb RAACI
publishDate 2014
url https://doaj.org/article/06cf4f3946f64cc3b21d9c52a17c2f71
work_keys_str_mv AT nvpiven autoantibodiestoglutamicaciddecarboxylaseasapathogeneticmarkeroftypeidiabetesmellitus
AT lnlukhverchyk autoantibodiestoglutamicaciddecarboxylaseasapathogeneticmarkeroftypeidiabetesmellitus
AT aiburakovsky autoantibodiestoglutamicaciddecarboxylaseasapathogeneticmarkeroftypeidiabetesmellitus
AT nvpolegenkaya autoantibodiestoglutamicaciddecarboxylaseasapathogeneticmarkeroftypeidiabetesmellitus
AT mvkarpovich autoantibodiestoglutamicaciddecarboxylaseasapathogeneticmarkeroftypeidiabetesmellitus
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