AUTOANTIBODIES TO GLUTAMIC ACID DECARBOXYLASE AS A PATHOGENETIC MARKER OF TYPE I DIABETES MELLITUS
Abstract. A new method of enzyme-linked immunosorbent assay (in solid-phase ELISA format) has been developed to determine concentrations of autoantibodies to glutamic acid decarboxylase, as well as an evidencebased methodology is proposed for its medical implications, as a quantitative pathogenetic...
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2014
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oai:doaj.org-article:06cf4f3946f64cc3b21d9c52a17c2f712021-11-18T08:03:41ZAUTOANTIBODIES TO GLUTAMIC ACID DECARBOXYLASE AS A PATHOGENETIC MARKER OF TYPE I DIABETES MELLITUS1563-06252313-741X10.15789/1563-0625-2011-2-3-257-260https://doaj.org/article/06cf4f3946f64cc3b21d9c52a17c2f712014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/511https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. A new method of enzyme-linked immunosorbent assay (in solid-phase ELISA format) has been developed to determine concentrations of autoantibodies to glutamic acid decarboxylase, as well as an evidencebased methodology is proposed for its medical implications, as a quantitative pathogenetic predictive marker of autoimmune diagnostics in type 1 diabetes mellitus. This technique could be implied for serial production of diagnostic reagent kits, aimed for detection of autoantibodies to glutamic acid decarboxylase by means of ELISA approach. (Med. Immunol., 2011, vol. 13, N 2-3, pp 257-260)N. V. PivenL. N. LukhverchykA. I. BurakovskyN. V. PolegenkayaM. V. KarpovichSPb RAACIarticleautoantibodiesglutamic acid decarboxylaseimmunoenzyme assaydiabetes mellituspathogenesisImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 13, Iss 2-3, Pp 257-260 (2014) |
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DOAJ |
language |
RU |
topic |
autoantibodies glutamic acid decarboxylase immunoenzyme assay diabetes mellitus pathogenesis Immunologic diseases. Allergy RC581-607 |
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autoantibodies glutamic acid decarboxylase immunoenzyme assay diabetes mellitus pathogenesis Immunologic diseases. Allergy RC581-607 N. V. Piven L. N. Lukhverchyk A. I. Burakovsky N. V. Polegenkaya M. V. Karpovich AUTOANTIBODIES TO GLUTAMIC ACID DECARBOXYLASE AS A PATHOGENETIC MARKER OF TYPE I DIABETES MELLITUS |
description |
Abstract. A new method of enzyme-linked immunosorbent assay (in solid-phase ELISA format) has been developed to determine concentrations of autoantibodies to glutamic acid decarboxylase, as well as an evidencebased methodology is proposed for its medical implications, as a quantitative pathogenetic predictive marker of autoimmune diagnostics in type 1 diabetes mellitus. This technique could be implied for serial production of diagnostic reagent kits, aimed for detection of autoantibodies to glutamic acid decarboxylase by means of ELISA approach. (Med. Immunol., 2011, vol. 13, N 2-3, pp 257-260) |
format |
article |
author |
N. V. Piven L. N. Lukhverchyk A. I. Burakovsky N. V. Polegenkaya M. V. Karpovich |
author_facet |
N. V. Piven L. N. Lukhverchyk A. I. Burakovsky N. V. Polegenkaya M. V. Karpovich |
author_sort |
N. V. Piven |
title |
AUTOANTIBODIES TO GLUTAMIC ACID DECARBOXYLASE AS A PATHOGENETIC MARKER OF TYPE I DIABETES MELLITUS |
title_short |
AUTOANTIBODIES TO GLUTAMIC ACID DECARBOXYLASE AS A PATHOGENETIC MARKER OF TYPE I DIABETES MELLITUS |
title_full |
AUTOANTIBODIES TO GLUTAMIC ACID DECARBOXYLASE AS A PATHOGENETIC MARKER OF TYPE I DIABETES MELLITUS |
title_fullStr |
AUTOANTIBODIES TO GLUTAMIC ACID DECARBOXYLASE AS A PATHOGENETIC MARKER OF TYPE I DIABETES MELLITUS |
title_full_unstemmed |
AUTOANTIBODIES TO GLUTAMIC ACID DECARBOXYLASE AS A PATHOGENETIC MARKER OF TYPE I DIABETES MELLITUS |
title_sort |
autoantibodies to glutamic acid decarboxylase as a pathogenetic marker of type i diabetes mellitus |
publisher |
SPb RAACI |
publishDate |
2014 |
url |
https://doaj.org/article/06cf4f3946f64cc3b21d9c52a17c2f71 |
work_keys_str_mv |
AT nvpiven autoantibodiestoglutamicaciddecarboxylaseasapathogeneticmarkeroftypeidiabetesmellitus AT lnlukhverchyk autoantibodiestoglutamicaciddecarboxylaseasapathogeneticmarkeroftypeidiabetesmellitus AT aiburakovsky autoantibodiestoglutamicaciddecarboxylaseasapathogeneticmarkeroftypeidiabetesmellitus AT nvpolegenkaya autoantibodiestoglutamicaciddecarboxylaseasapathogeneticmarkeroftypeidiabetesmellitus AT mvkarpovich autoantibodiestoglutamicaciddecarboxylaseasapathogeneticmarkeroftypeidiabetesmellitus |
_version_ |
1718422461248176128 |