Anti-AMPA GluA3 antibodies in Frontotemporal dementia: a new molecular target

Anti-AMPA GluA3 antibodies in Frontotemporal dementia: a new molecular target

Abstract Frontotemporal Dementia (FTD) is a neurodegenerative disorder mainly characterised by Tau or TDP43 inclusions. A co-autoimmune aetiology has been hypothesised. In this study, we aimed at defining the pathogenetic role of anti-AMPA GluA3 antibodies in FTD. Serum and cerebrospinal fluid (CSF)...

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Main Authors: B. Borroni, J. Stanic, C. Verpelli, M. Mellone, E. Bonomi, A. Alberici, P. Bernasconi, L. Culotta, E. Zianni, S. Archetti, M. Manes, S. Gazzina, R. Ghidoni, L. Benussi, C. Stuani, M. Di Luca, C. Sala, E. Buratti, A. Padovani, F. Gardoni
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/06d950f123f848ba8e85a6894e3d8dd6
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