Thymic iNKT single cell analyses unmask the common developmental program of mouse innate T cells

Innate-like T cells such as invariant natural killer T (iNKT) and mucosal-associated invariant T (MAIT) cells both develop in the thymus. Here the authors use single-cell RNA sequencing to show that mouse iNKT and MAIT share components of developmental regulation, with a transcription factor, Hivep3...

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Autores principales: S. Harsha Krovi, Jingjing Zhang, Mary Jessamine Michaels-Foster, Tonya Brunetti, Liyen Loh, James Scott-Browne, Laurent Gapin
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/06e13866d71d4727a0acfddef21305ab
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