Enteric reabsorption processes and their impact on drug pharmacokinetics

Abstract Enteric reabsorption occurs when a drug is secreted into the intestinal lumen and reabsorbed into the systemic circulation. This distribution process is evidenced by multiple peaks in pharmacokinetic profiles. Commonly, hepatobiliary drug secretion is assumed to be the underlying mechanism...

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Autores principales: Manuel Ibarra, Iñaki F. Trocóniz, Pietro Fagiolino
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/06f6fe54abf34410957ca74df2962c43
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