Reduced crowding and poor contour detection in schizophrenia are consistent with weak surround inhibition.

<h4>Background</h4>Detection of visual contours (strings of small oriented elements) is markedly poor in schizophrenia. This has previously been attributed to an inability to group local information across space into a global percept. Here, we show that this failure actually originates f...

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Autores principales:	Valentina Robol, Marc S Tibber, Elaine J Anderson, Tracy Bobin, Patricia Carlin, Sukhwinder S Shergill, Steven C Dakin
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2013
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/06fa2b9920224287bb7aa6feac83984b
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spelling	oai:doaj.org-article:06fa2b9920224287bb7aa6feac83984b2021-11-18T07:50:04ZReduced crowding and poor contour detection in schizophrenia are consistent with weak surround inhibition.1932-620310.1371/journal.pone.0060951https://doaj.org/article/06fa2b9920224287bb7aa6feac83984b2013-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23585865/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Background</h4>Detection of visual contours (strings of small oriented elements) is markedly poor in schizophrenia. This has previously been attributed to an inability to group local information across space into a global percept. Here, we show that this failure actually originates from a combination of poor encoding of local orientation and abnormal processing of visual context.<h4>Methods</h4>We measured the ability of observers with schizophrenia to localise contours embedded in backgrounds of differently oriented elements (either randomly oriented, near-parallel or near-perpendicular to the contour). In addition, we measured patients' ability to process local orientation information (i.e., report the orientation of an individual element) for both isolated and crowded elements (i.e., presented with nearby distractors).<h4>Results</h4>While patients are poor at detecting contours amongst randomly oriented elements, they are proportionally less disrupted (compared to unaffected controls) when contour and surrounding elements have similar orientations (near-parallel condition). In addition, patients are poor at reporting the orientation of an individual element but, again, are less prone to interference from nearby distractors, a phenomenon known as visual crowding.<h4>Conclusions</h4>We suggest that patients' poor performance at contour perception arises not as a consequence of an "integration deficit" but from a combination of reduced sensitivity to local orientation and abnormalities in contextual processing. We propose that this is a consequence of abnormal gain control, a phenomenon that has been implicated in orientation-selectivity as well as surround suppression.Valentina RobolMarc S TibberElaine J AndersonTracy BobinPatricia CarlinSukhwinder S ShergillSteven C DakinPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 8, Iss 4, p e60951 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Valentina Robol Marc S Tibber Elaine J Anderson Tracy Bobin Patricia Carlin Sukhwinder S Shergill Steven C Dakin Reduced crowding and poor contour detection in schizophrenia are consistent with weak surround inhibition.
description	<h4>Background</h4>Detection of visual contours (strings of small oriented elements) is markedly poor in schizophrenia. This has previously been attributed to an inability to group local information across space into a global percept. Here, we show that this failure actually originates from a combination of poor encoding of local orientation and abnormal processing of visual context.<h4>Methods</h4>We measured the ability of observers with schizophrenia to localise contours embedded in backgrounds of differently oriented elements (either randomly oriented, near-parallel or near-perpendicular to the contour). In addition, we measured patients' ability to process local orientation information (i.e., report the orientation of an individual element) for both isolated and crowded elements (i.e., presented with nearby distractors).<h4>Results</h4>While patients are poor at detecting contours amongst randomly oriented elements, they are proportionally less disrupted (compared to unaffected controls) when contour and surrounding elements have similar orientations (near-parallel condition). In addition, patients are poor at reporting the orientation of an individual element but, again, are less prone to interference from nearby distractors, a phenomenon known as visual crowding.<h4>Conclusions</h4>We suggest that patients' poor performance at contour perception arises not as a consequence of an "integration deficit" but from a combination of reduced sensitivity to local orientation and abnormalities in contextual processing. We propose that this is a consequence of abnormal gain control, a phenomenon that has been implicated in orientation-selectivity as well as surround suppression.
format	article
author	Valentina Robol Marc S Tibber Elaine J Anderson Tracy Bobin Patricia Carlin Sukhwinder S Shergill Steven C Dakin
author_facet	Valentina Robol Marc S Tibber Elaine J Anderson Tracy Bobin Patricia Carlin Sukhwinder S Shergill Steven C Dakin
author_sort	Valentina Robol
title	Reduced crowding and poor contour detection in schizophrenia are consistent with weak surround inhibition.
title_short	Reduced crowding and poor contour detection in schizophrenia are consistent with weak surround inhibition.
title_full	Reduced crowding and poor contour detection in schizophrenia are consistent with weak surround inhibition.
title_fullStr	Reduced crowding and poor contour detection in schizophrenia are consistent with weak surround inhibition.
title_full_unstemmed	Reduced crowding and poor contour detection in schizophrenia are consistent with weak surround inhibition.
title_sort	reduced crowding and poor contour detection in schizophrenia are consistent with weak surround inhibition.
publisher	Public Library of Science (PLoS)
publishDate	2013
url	https://doaj.org/article/06fa2b9920224287bb7aa6feac83984b
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Reduced crowding and poor contour detection in schizophrenia are consistent with weak surround inhibition.

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